A8FWD6 (A8FWD6_SHESH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP MF_00137
EC=6.3.2.6 HAMAP MF_00137

Alternative name(s):
SAICAR synthetase HAMAP MF_00137

Gene names

Name:	purC HAMAP MF_00137
Ordered Locus Names:	Ssed_2552

Organism

Shewanella sediminis (strain HAW-EB3) [Complete proteome] [HAMAP] EMBL ABV37159.1

Taxonomic identifier

425104 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	368 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP MF_00137
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP MF_00137
Sequence similarities	Belongs to the SAICAR synthetase family. HAMAP MF_00137

Ontologies

Keywords
Biological process	Purine biosynthesis HAMAP MF_00137
Ligand	ATP-binding HAMAP MF_00137 Nucleotide-binding
Molecular function	Ligase HAMAP MF_00137 EMBL ABV37159.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8FWD6 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: B51AEA3EB493A634	FASTA	368	41,243
	10 20 30 40 50 60 MNLSNKVLAV NDDLPIRTDK AVHSGKVRSV YWLTEQDSAR LIKDKGYDVP ANTPLAIMVI 70 80 90 100 110 120 SDRISAFDCI WQGEDGLNGV PGKGAALNAI SNHWFKLFKE KGLADSHILD VPHPFVWIVQ 130 140 150 160 170 180 KAQPVMVEAI ARQYITGSMW RAYTKGEREF CGITLPEGLE KDQKLPELLI TPSTKGVLTG 190 200 210 220 230 240 LEGVPEADDV NVSRSDLERH LEGFNFHNAS DIDLYEKLLK EGFGVISDAL AAQDQIFIDT 250 260 270 280 290 300 KFEFGYVNGA DGKEKLIYMD EVGTPDSSRI WDGPAHRDGQ IIEKSKEGFR QWLLNHFPDS 310 320 330 340 350 360 DILLNKERMP ERFALAADNK LPQSVMMDIS NTYVGIAEKV IGEKLTISEN PKQEIIDILR NEYQLIAD

References

[1]

"Complete sequence of Shewanella sediminis HAW-EB3." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Zhao J.-S., Richardson P. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HAW-EB3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000821 Genomic DNA. Translation: ABV37159.1.
RefSeq	YP_001474287.1. NC_009831.1.
3D structure databases
ProteinModelPortal	A8FWD6.
ModBase	Search...
Protein-protein interaction databases
STRING	A8FWD6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5609723.
GenomeReviews	Gene locus Ssed_2552 in contig CP000821_GR.
KEGG	sse:Ssed_2552.
NMPDR	fig|425104.3.peg.2259.
PATRIC	23562773. VBISheSed62411_2725.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0152.
HOGENOM	HBG555040.
OMA	SSRIWDG.
ProtClustDB	PRK13960.
Enzyme and pathway databases
BioCyc	SSED425104:SSED_2552-MONOMER.
Family and domain databases
HAMAP	MF_00137. SAICAR_synth. [Tree]
InterPro	IPR013816. ATP_grasp_subdomain_2. IPR014106. PurC_vibrio. IPR001636. SAICAR_synth. [Graphical view]
Gene3D	G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KO	K01923.
PANTHER	PTHR11609. SAICAR_synt. 1 hit.
Pfam	PF01259. SAICAR_synt. 1 hit. [Graphical view]
TIGRFAMs	TIGR02735. PurC_vibrio. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8FWD6_SHESH

Accession

Primary (citable) accession number: A8FWD6

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)