A8FUU2 (A8FUU2_SHESH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163

Gene names

Name:	def2 HAMAP MF_00163
Ordered Locus Names:	Ssed_2006

Organism

Shewanella sediminis (strain HAW-EB3) [Complete proteome] [HAMAP] EMBL ABV36615.1

Taxonomic identifier

425104 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. HAMAP MF_00163

Ontologies

Keywords
Biological process	Protein biosynthesis SAAS SAAS000181 HAMAP MF_00163
Ligand	Iron HAMAP MF_00163 Metal-binding HAMAP MF_00163 SAAS SAAS000181
Molecular function	Hydrolase HAMAP MF_00163 SAAS SAAS000181 EMBL ABV36615.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	134	1	By similarity HAMAP MF_00163
	Metal binding	91	1	Iron By similarity HAMAP MF_00163
	Metal binding	133	1	Iron By similarity HAMAP MF_00163
	Metal binding	137	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	A8FUU2 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 27130AD26A2A80BF	FASTA	163	18,183
	10 20 30 40 50 60 MAVLDILTIP DERLKRKAQP VKDIESVQGF IDDLLDTMYD TEDGIGLAAT QVGSLHAILV 70 80 90 100 110 120 IDLSPERDQP QVLINPEIIE AEGDFVGEEG CLSIPGYRAK VTRSEKVKIK ALDRTGTPFE 130 140 150 160 IETDTFLAIV IQHEMEHLQG VVFTDHLSKL KQQIALKKVS KYK

References

[1]

"Complete sequence of Shewanella sediminis HAW-EB3." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Zhao J.-S., Richardson P. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HAW-EB3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000821 Genomic DNA. Translation: ABV36615.1.
RefSeq	YP_001473743.1. NC_009831.1.
3D structure databases
ProteinModelPortal	A8FUU2.
SMR	A8FUU2. Positions 2-162.
ModBase	Search...
Protein-protein interaction databases
STRING	A8FUU2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5612152.
GenomeReviews	Gene locus Ssed_2006 in contig CP000821_GR.
KEGG	sse:Ssed_2006.
NMPDR	fig|425104.3.peg.1770.
PATRIC	23561522. VBISheSed62411_2135.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0242.
HOGENOM	HBG665227.
OMA	MINAHIE.
ProtClustDB	PRK12846.
Enzyme and pathway databases
BioCyc	SSED425104:SSED_2006-MONOMER.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8FUU2_SHESH

Accession

Primary (citable) accession number: A8FUU2

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)