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A8FN77 (PGK_CAMJ8) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:C8J_1316
OrganismCampylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828) [Complete proteome] [HAMAP]
Taxonomic identifier407148 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000203325

Regions

Nucleotide binding353 – 3564ATP By similarity
Region22 – 243Substrate binding By similarity
Region61 – 644Substrate binding By similarity

Sites

Binding site381Substrate By similarity
Binding site1191Substrate By similarity
Binding site1521Substrate By similarity
Binding site2051ATP By similarity
Binding site2961ATP; via carbonyl oxygen By similarity
Binding site3271ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
A8FN77 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 46B2FD9F39F87FB2

FASTA40043,605
        10         20         30         40         50         60 
MSDIISIKDI DLAKKKVFIR CDFNVPQDDF LNITDDRRIR SAIPTIRYCL DNGCSVILAS 

        70         80         90        100        110        120 
HLGRPKEISS KYSLEPVAKR LARLLDKEII MAKDVIGEDA KTKAMNLKAG EILLLENLRF 

       130        140        150        160        170        180 
EKGETKNDEN LAKELASMVQ VYINDAFGVC HRAHSSVEAI TKFFDEKHKG AGFLLQKEID 

       190        200        210        220        230        240 
FASNLIKHPA RPFVAVVGGS KVSGKLQALT NLLPKVDKLI IGGGMAFTFL KALGYDIGNS 

       250        260        270        280        290        300 
LLEEELLEEA NKILTKGKNL GVKIYLPVDV VAAPACSQDA PMKFVPVQEI PNGWMGLDIG 

       310        320        330        340        350        360 
PASVRLFKEV ISDAQTIWWN GPMGVFEIDK FSKGSIKMSH YISEGHATSV VGGGDTADVV 

       370        380        390        400 
ARAGDADEMT FISTGGGASL ELIEGKELPG VKALRSKENE 

« Hide

References

[1]"The complete genome sequence of Campylobacter jejuni strain 81116 (NCTC11828)."
Pearson B.M., Gaskin D.J.H., Segers R.P.A.M., Wells J.M., Nuijten P.J.M., van Vliet A.H.M.
J. Bacteriol. 189:8402-8403(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 81116 / NCTC 11828.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000814 Genomic DNA. Translation: ABV52914.1.
RefSeqYP_001482891.1. NC_009839.1.

3D structure databases

ProteinModelPortalA8FN77.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING407148.C8J_1316.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV52914; ABV52914; C8J_1316.
GeneID5618531.
KEGGcju:C8J_1316.
PATRIC20056270. VBICamJej119085_1325.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAMSIRYID.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycCJEJ407148:GHCS-1354-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_CAMJ8
AccessionPrimary (citable) accession number: A8FN77
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: November 13, 2007
Last modified: June 11, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways