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A8FKQ5 (EFTU_CAMJ8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Elongation factor Tu
Short name=EF-Tu
Gene names
Name:tuf
Ordered Locus Names:C8J_0443
OrganismCampylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828) [Complete proteome] [HAMAP]
Taxonomic identifier407148 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter ›

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processGTP catabolic process

Inferred from electronic annotation. Source: GOC

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Elongation factor Tu HAMAP-Rule MF_00118
PRO_1000071360

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding81 – 855GTP By similarity
Nucleotide binding136 – 1394GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
A8FKQ5 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 0FAF86F46938AAA9

FASTA39943,594
        10         20         30         40         50         60 
MAKEKFSRNK PHVNIGTIGH VDHGKTTLTA AISAVLSRRG LAELKDYDNI DNAPEEKERG 

        70         80         90        100        110        120 
ITIATSHIEY ETDNRHYAHV DCPGHADYVK NMITGAAQMD GAILVVSAAD GPMPQTREHI 

       130        140        150        160        170        180 
LLSRQVGVPY IVVFMNKADM VDDAELLELV EMEIRELLSS YDFPGDDTPI ISGSALKALE 

       190        200        210        220        230        240 
EAKAGQDGEW SAKIMDLMAA VDSYIPTPTR DTEKDFLMPI EDVFSISGRG TVVTGRIEKG 

       250        260        270        280        290        300 
VVKVGDTIEI VGIKDTQTTT VTGVEMFRKE MDQGEAGDNV GVLLRGTKKE EVIRGMVLAK 

       310        320        330        340        350        360 
PKSITPHTDF EAEVYILNKD EGGRHTPFFN NYRPQFYVRT TDVTGSIKLA DGVEMVMPGE 

       370        380        390 
NVRITVSLIA PVALEEGTRF AIREGGKTVG SGVVSKIIK

« Hide

References

[1]"The complete genome sequence of Campylobacter jejuni strain 81116 (NCTC11828)."
Pearson B.M., Gaskin D.J.H., Segers R.P.A.M., Wells J.M., Nuijten P.J.M., van Vliet A.H.M.
J. Bacteriol. 189:8402-8403(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 81116 / NCTC 11828.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000814 Genomic DNA. Translation: ABV52042.1.
RefSeqYP_001482019.1. NC_009839.1.

3D structure databases

ProteinModelPortalA8FKQ5.
SMRA8FKQ5. Positions 2-398.
ModBaseSearch...

Protein-protein interaction databases

STRING407148.C8J_0443.

Proteomic databases

PRIDEA8FKQ5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV52042; ABV52042; C8J_0443.
GeneID5617842.
KEGGcju:C8J_0443.
PATRIC20054476. VBICamJej119085_0452.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMAHTDFEAN.
ProtClustDBPRK12735.

Enzyme and pathway databases

BioCycCJEJ407148:GHCS-487-MONOMER.

Family and domain databases

HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR005225. Small_GTP-bd_dom.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
IPR009000. Transl_elong_init/rib_B-barrel.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50465. Elong_init_C. 1 hit.
SSF50447. Translat_factor. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_CAMJ8
AccessionPrimary (citable) accession number: A8FKQ5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: November 13, 2007
Last modified: May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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