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A8FIG8 (SYR_BACP2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:BPUM_3383
OrganismBacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]
Taxonomic identifier315750 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length557 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 557557Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000057807

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A8FIG8 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 4CB8A859ABC92D67

FASTA55762,734
        10         20         30         40         50         60 
MNIAEQVKDA LKEEIIAAVV KAGLADESQV PDVLLEVPKD KTHGDYSTNM AMQLARIAKK 

        70         80         90        100        110        120 
APRQIAEDIV KAFDKGKASI EKMDIAGPGF INFYMNNQYL TKLIPAVLEA KEAYGETNTG 

       130        140        150        160        170        180 
GGQKVQVEFV SANPTGDLHL GHARGAAVGD SLCNILDKAG FDVSREYYIN DAGNQINNLA 

       190        200        210        220        230        240 
LSVEVRYFEA LGLEKEMPED GYRGEDIKGI GQKLADEFGD RFVHESEEER MKFFREYGLK 

       250        260        270        280        290        300 
YELEKLRVDL ENFRVPFDVW YSETSLYENG KIEPALETLR EKGYVFEEDG ATWLRSTDFG 

       310        320        330        340        350        360 
DDKDRVLIKK DGSFTYLLPD IAYHKDKLDR GFDQLINIWG ADHHGYIPRM KAAIQALGYP 

       370        380        390        400        410        420 
AGKLEVEIIQ LVHLYKNGEK MKMSKRTGKA VTMRDLIEEV GLDATRYFFA MRSAATHMDF 

       430        440        450        460        470        480 
DLDLAISTSN ENPVYYAQYA HARICSMLRQ GEEKGYEPNL EKADFSHIQS EKEYDLLKII 

       490        500        510        520        530        540 
GGFPEVVAEA AEKRIPHRVT NYIYDLASAL HSFYNAEKVI DVENETKTTA RLSLMKATQI 

       550 
TLANALKLIG VSAPEKM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000813 Genomic DNA. Translation: ABV64035.1.
RefSeqYP_001488595.1. NC_009848.1.

3D structure databases

ProteinModelPortalA8FIG8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315750.BPUM_3383.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV64035; ABV64035; BPUM_3383.
GeneID5622678.
KEGGbpu:BPUM_3383.
PATRIC18970732. VBIBacPum16546_3435.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMALCNVLAK.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycBPUM315750:GH6N-3465-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_BACP2
AccessionPrimary (citable) accession number: A8FIG8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries