A8FID4 (A8FID4_BACP2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) EMBL ABV64001.1
EC=1.1.1.40 EMBL ABV64001.1

Gene names

Name:	ywkA EMBL ABV64001.1
Ordered Locus Names:	BPUM_3348

Organism

Bacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]

Taxonomic identifier

315750 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	566 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the malic enzymes family. RuleBase RU003427

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003427
Molecular function	Oxidoreductase RuleBase RU003427 EMBL ABV64001.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	malate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (oxaloacetate-decarboxylating) activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8FID4 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 3C1B840BB4105E43	FASTA	566	62,364
	10 20 30 40 50 60 MNNVKKTKEG YLETTLTGKD VLSIPTLNKG VAFSEEERQE LGLEGLLPPT VLTLEQQAER 70 80 90 100 110 120 AYKQFLAQPD RLRQNVYLSD LQNRNEVLFY KLISDKLREM LPVVYTPTVG EAIQEYSHEY 130 140 150 160 170 180 RRPHGVYLSI DNIDGIEKAF ENLHATAGDI DLIVATDSES ILGIGDWGVG GINIAIGKLA 190 200 210 220 230 240 VYTAAAGIDP SRVIPVVLDV GTNNEKLLND PLYIGNHHKR VQGEKYEEFI DAYVKAALKF 250 260 270 280 290 300 FPKALLHWED LGNKNARNIM KKYNDNILTF NDDIQGTGAI TLAGVLAAVK KTGTQLKDHR 310 320 330 340 350 360 VMIFGAGSAG IGIADQMRDT MVLEGLTEEE ANNAFWTLDY RGLLTDQFED EVFDFQKPYL 370 380 390 400 410 420 RSSDEVEGWA RDEKGQISFA EAVRQVKPTI LIGTSGQGGA FTEEIIKEIA AHTERPVIMP 430 440 450 460 470 480 MSNPTPLAEA VPEDLFKWTD GRALVATGSP FENVEYNGIE HEIGQSNNAF VFPGLGLGSI 490 500 510 520 530 540 VTESKIITKG MFVASADAIA EMVDHDKPGA GLLPSIDKLQ EVSIKVAIEV AKAAIKDGVA 550 560 RKTPDDIEQA VKDAMWIPEY KKIVRA

References

[1]

"Paradoxical DNA repair and peroxide resistance gene conservation in Bacillus pumilus SAFR-032." Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D., Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H., Lee S., Nazareth L., Blyth P., Holder M., Buhay C. , Tirumalai M.R., Liu Y., Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P., Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D., Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F., Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K., Weinstock G.M. PLoS ONE 2:E928-E928(2007) [PubMed: 17895969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000813 Genomic DNA. Translation: ABV64001.1.
RefSeq	YP_001488561.1. NC_009848.1.
3D structure databases
ProteinModelPortal	A8FID4.
ModBase	Search...
Protein-protein interaction databases
STRING	A8FID4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000065194; EBBACP00000063527; EBBACG00000065185.
GeneID	5622643.
GenomeReviews	Gene locus BPUM_3348 in contig CP000813_GR.
KEGG	bpu:BPUM_3348.
PATRIC	18970658. VBIBacPum16546_3398.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0281.
GeneTree	EBGT00050000001535.
HOGENOM	HBG289821.
OMA	NARNIMK.
ProtClustDB	PRK13529.
Family and domain databases
InterPro	IPR015884. Malic_enzyme_CS. IPR012301. Malic_N. IPR012302. Malic_NAD-bd. IPR001891. Malic_OxRdtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.10380. G3DSA:3.40.50.10380. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00027.
Pfam	PF00390. malic. 1 hit. PF03949. Malic_M. 1 hit. [Graphical view]
PIRSF	PIRSF000106. ME. 1 hit.
PRINTS	PR00072. MALOXRDTASE.
SMART	SM00919. Malic_M. 1 hit. [Graphical view]
PROSITE	PS00331. MALIC_ENZYMES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8FID4_BACP2

Accession

Primary (citable) accession number: A8FID4

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)