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Protein

Uronate isomerase

Gene

uxaC

Organism
Bacillus pumilus (strain SAFR-032)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciBPUM315750:GH6N-3068-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:BPUM_2987
OrganismiBacillus pumilus (strain SAFR-032)
Taxonomic identifieri315750 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001355 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 478478Uronate isomerasePRO_1000061949Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi315750.BPUM_2987.

Structurei

3D structure databases

ProteinModelPortaliA8FHC4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

A8FHC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAFLNEQFL LNSPTAEKLY HEFAKDLPII DYHCHLSPKD IYENKTFRNI
60 70 80 90 100
TEAWLYGDHY KWRAMRANGI PETHVTGDAS DYDKFLAWAK TVPMTIGNPL
110 120 130 140 150
YHWTHLELRR YFEVQDLLNE KNADTIWQKV NEKLQEEGFG ARDFIMKSNV
160 170 180 190 200
ETVVTTDDPI DSLQYHQKLR EEGFSVQVLP GFRPDKALDI ANDLFEKYVH
210 220 230 240 250
ELAEASAISI QSYQDFLNAL RARIDFFHEH GCLISDHAIN EMTYEETTQE
260 270 280 290 300
EVETIFHKRM SGYPLTEKEK IKFKTETFIM LGQAYCERGW AMQLHINALR
310 320 330 340 350
NNNTKMFERL GPDTGYDAMN DEDIAKPLCR ILDRLEQEDA LPNTILYSLN
360 370 380 390 400
PRDNVVISTL AGSFQDGKTP GKMQHGTAWW FNDTKQGMTE QMMTLSSIGL
410 420 430 440 450
ISRFIGMLTD SRSFLSYTRH EYFRRLLCDI IGDWVEKGEV PYDLELLGEI
460 470
VKGISYENAK QYFQFDRVKQ LHHQSKIT
Length:478
Mass (Da):55,773
Last modified:November 13, 2007 - v1
Checksum:iA3595574FC38C245
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000813 Genomic DNA. Translation: ABV63641.1.
RefSeqiWP_012011237.1. NC_009848.4.

Genome annotation databases

EnsemblBacteriaiABV63641; ABV63641; BPUM_2987.
KEGGibpu:BPUM_2987.
PATRICi18969956. VBIBacPum16546_3048.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000813 Genomic DNA. Translation: ABV63641.1.
RefSeqiWP_012011237.1. NC_009848.4.

3D structure databases

ProteinModelPortaliA8FHC4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315750.BPUM_2987.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV63641; ABV63641; BPUM_2987.
KEGGibpu:BPUM_2987.
PATRICi18969956. VBIBacPum16546_3048.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciBPUM315750:GH6N-3068-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_BACP2
AccessioniPrimary (citable) accession number: A8FHC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: September 7, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.