A8FG71 (A8FG71_BACP2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetate kinase HAMAP MF_00020
EC=2.7.2.1 HAMAP MF_00020

Alternative name(s):
Acetokinase HAMAP MF_00020

Gene names

Name:	ackA HAMAP MF_00020 EMBL ABV63238.1
Ordered Locus Names:	BPUM_2579

Organism

Bacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]

Taxonomic identifier

315750 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 SAAS SAAS000890 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020 SAAS SAAS000890
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family. HAMAP MF_00020 RuleBase RU003835

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00020 SAAS SAAS000890
Ligand	ATP-binding HAMAP MF_00020 SAAS SAAS000890 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00020 SAAS SAAS000890 RuleBase RU003835 EMBL ABV63238.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8FG71 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 28B095AD23DEFC90	FASTA	394	43,179
	10 20 30 40 50 60 MSKIIAINAG SSSLKFQLFD MPEETVLTKG LVERIGMDNS IFTISVDGEK KTEVTDIPDH 70 80 90 100 110 120 AVAVKMLLEK LIEFNIIKDF NEIDGVGHRV VHGGEKFSDS VLLTDEVIND IDQLSELAPL 130 140 150 160 170 180 HNPANVVGIK AFKQILPDVP AIAVFDTAFH QTMPEQSYLY SLPYDYYKNF GIRKYGFHGT 190 200 210 220 230 240 SHKFVTERAS ELLGRPLEEL RLISCHLGNG ASIAAVEGGR SIDTSMGFTP LAGVAMGTRS 250 260 270 280 290 300 GNIDPALIPF IMEKTGHTAE EVLSTLNKKS GLLGVSGLSS DLRDIEEATE EGNDRAEVAL 310 320 330 340 350 360 DIFASRIHKY IGSYAARMNG VDAIIFTAGI GENSSEVRAR VLRGLEFMGV YWDPSLNNMR 370 380 390 GEEAFISYPH SPVKVIVIPT NEEVMIARDV MRLA

References

[1]

"Paradoxical DNA repair and peroxide resistance gene conservation in Bacillus pumilus SAFR-032." Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D., Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H., Lee S., Nazareth L., Blyth P., Holder M., Buhay C. , Tirumalai M.R., Liu Y., Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P., Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D., Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F., Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K., Weinstock G.M. PLoS ONE 2:E928-E928(2007) [PubMed: 17895969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000813 Genomic DNA. Translation: ABV63238.1.
RefSeq	YP_001487798.1. NC_009848.1.
3D structure databases
ProteinModelPortal	A8FG71.
SMR	A8FG71. Positions 3-393.
ModBase	Search...
Protein-protein interaction databases
STRING	A8FG71.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000064051; EBBACP00000062384; EBBACG00000064042.
GeneID	5621849.
GenomeReviews	Gene locus BPUM_2579 in contig CP000813_GR.
KEGG	bpu:BPUM_2579.
PATRIC	18969088. VBIBacPum16546_2638.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
GeneTree	EBGT00050000000769.
HOGENOM	HBG285863.
OMA	LIDMTNE.
ProtClustDB	PRK00180.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8FG71_BACP2

Accession

Primary (citable) accession number: A8FG71

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)