A8FFY8 (MURI_BACP2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	BPUM_2493

Organism

Bacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]

Taxonomic identifier

315750 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	272 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 272	272	Glutamate racemase HAMAP MF_00258		PRO_1000059065

Sequences

	Sequence		Length	Mass (Da)
	A8FFY8 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 8061BF38F69D2CEA	FASTA	272	29,948
	10 20 30 40 50 60 MLDQPIGVID SGVGGLTVAK EIMRQLPKEK IIYVGDTKRC PYGPRKEEEV LQYTWEMAHY 70 80 90 100 110 120 LLRHHHIKML VIACNTATAI ALDEIKATLD IPVIGVIQPG ARTAIKVTNN QQIGVIGTAN 130 140 150 160 170 180 TIKSEAYKEA LLSLKAGLAV QSLACPLLVP FVESGTFLDQ TADEVVKDSL EPMKETGIDT 190 200 210 220 230 240 LILGCTHYPI LKESIQRFMG SDVSIISSGD ETAREASTIL SYKGLLNTSQ EAPVHTFYTT 250 260 270 GQQQNFENIA RDWFGYLPGK VETVSLEHVY QQ

References

[1]

"Paradoxical DNA repair and peroxide resistance gene conservation in Bacillus pumilus SAFR-032." Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D., Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H., Lee S., Nazareth L., Blyth P., Holder M., Buhay C. , Tirumalai M.R., Liu Y., Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P., Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D., Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F., Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K., Weinstock G.M. PLoS ONE 2:E928-E928(2007) [PubMed: 17895969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SAFR-032.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000813 Genomic DNA. Translation: ABV63155.1.
RefSeq	YP_001487715.1. NC_009848.1.
3D structure databases
ProteinModelPortal	A8FFY8.
SMR	A8FFY8. Positions 1-266.
ModBase	Search...
Protein-protein interaction databases
STRING	A8FFY8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000063486; EBBACP00000061819; EBBACG00000063477.
GeneID	5621763.
GenomeReviews	Gene locus BPUM_2493 in contig CP000813_GR.
KEGG	bpu:BPUM_2493.
PATRIC	18968910. VBIBacPum16546_2549.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0796.
GeneTree	EBGT00050000002346.
HOGENOM	HBG645102.
OMA	PQEDTIY.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	BPUM315750:BPUM_2493-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_BACP2

Accession

Primary (citable) accession number: A8FFY8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program