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A8FFY6 (RNPH_BACP2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease PH

Short name=RNase PH
EC=2.7.7.56
Alternative name(s):
tRNA nucleotidyltransferase
Gene names
Name:rph
Ordered Locus Names:BPUM_2491
OrganismBacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]
Taxonomic identifier315750 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillus

Protein attributes

Sequence length242 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates By similarity. HAMAP MF_00564

Catalytic activity

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. HAMAP MF_00564

Sequence similarities

Belongs to the RNase PH family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 242242Ribonuclease PH HAMAP MF_00564
PRO_1000061129

Sequences

Sequence LengthMass (Da)Tools
A8FFY6 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 36C5ADADFDD02F00

FASTA24226,551
        10         20         30         40         50         60 
MRLDERHYDE LRKIEIEAGY ITHPEGSVLI SAGNTKVICN ASIEDRVPPF LRGEGKGWIT 

        70         80         90        100        110        120 
AEYSMLPRAT AQRTIRESSK GKVTGRTMEI QRLIGRALRA VVDLEKLGER TIWIDCDVIQ 

       130        140        150        160        170        180 
ADGGTRTASI TGAFVAMTLA IQKLRAEGAI KQNPITDYLA AISVGIDSQQ GLLLDLNYEE 

       190        200        210        220        230        240 
DSSAEVDMNV IMTGAGRFVE LQGTGEEATF SREQLNGLLD LAEKGIKELI EKQKAVTGEV 


IE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000813 Genomic DNA. Translation: ABV63153.1.
RefSeqYP_001487713.1. NC_009848.1.

3D structure databases

ProteinModelPortalA8FFY6.
SMRA8FFY6. Positions 1-239.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8FFY6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000064039; EBBACP00000062372; EBBACG00000064030.
GeneID5621761.
GenomeReviewsGene locus BPUM_2491 in contig CP000813_GR.
KEGGbpu:BPUM_2491.
PATRIC18968906. VBIBacPum16546_2547.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0689.
GeneTreeEBGT00050000001825.
HOGENOMHBG737187.
OMAMLPRATG.
ProtClustDBPRK00173.

Enzyme and pathway databases

BioCycBPUM315750:BPUM_2491-MONOMER.

Family and domain databases

HAMAPMF_00564. RNase_PH.
[Tree]
InterProIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
KOK00989.
PfamPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMSSF55666. 3_ExoRNase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR01966. RNasePH. 1 hit.
PROSITEPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNPH_BACP2
AccessionPrimary (citable) accession number: A8FFY6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families