Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Anti-sigma F factor

Gene

spoIIAB

Organism
Bacillus pumilus (strain SAFR-032)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
Biological processSporulation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma F factorUniRule annotation (EC:2.7.11.1UniRule annotation)
Alternative name(s):
Stage II sporulation protein ABUniRule annotation
Gene namesi
Name:spoIIABUniRule annotation
Ordered Locus Names:BPUM_2077
OrganismiBacillus pumilus (strain SAFR-032)
Taxonomic identifieri315750 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001355 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000614451 – 146Anti-sigma F factorAdd BLAST146

Proteomic databases

PRIDEiA8FET0.

Interactioni

Protein-protein interaction databases

STRINGi315750.BPUM_2077.

Structurei

3D structure databases

ProteinModelPortaliA8FET0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anti-sigma-factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZBE. Bacteria.
COG2172. LUCA.
HOGENOMiHOG000269931.
KOiK06379.
OMAiHAYEDKI.
OrthoDBiPOG091B004X.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
HAMAPiMF_00637. Anti_sigma_F. 1 hit.
InterProiView protein in InterPro
IPR010194. Anti-sigma_F.
IPR003594. HATPase_C.
PfamiView protein in Pfam
PF13581. HATPase_c_2. 1 hit.
SMARTiView protein in SMART
SM00387. HATPase_c. 1 hit.
SUPFAMiSSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR01925. spIIAB. 1 hit.

Sequencei

Sequence statusi: Complete.

A8FET0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNEMNLTFS ALSQNESFAR VTVAAFIAQL DPTLDELTEI KTVVSEAVTN
60 70 80 90 100
SIIHGYDGNP DGKVHIEVTL DDHVVYLTIR DEGMGITDLE EARQPLFTTK
110 120 130 140
PDLERSGMGF TIMENFMDDV MIDSSPEMGT TIRLTKHLSK SKALCN
Length:146
Mass (Da):16,240
Last modified:November 13, 2007 - v1
Checksum:i1A9DC9FF7E4A255F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000813 Genomic DNA. Translation: ABV62747.1.
RefSeqiWP_012010447.1. NC_009848.4.

Genome annotation databases

KEGGibpu:BPUM_2077.
PATRICi18968052. VBIBacPum16546_2122.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000813 Genomic DNA. Translation: ABV62747.1.
RefSeqiWP_012010447.1. NC_009848.4.

3D structure databases

ProteinModelPortaliA8FET0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315750.BPUM_2077.

Proteomic databases

PRIDEiA8FET0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGibpu:BPUM_2077.
PATRICi18968052. VBIBacPum16546_2122.

Phylogenomic databases

eggNOGiENOG4108ZBE. Bacteria.
COG2172. LUCA.
HOGENOMiHOG000269931.
KOiK06379.
OMAiHAYEDKI.
OrthoDBiPOG091B004X.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
HAMAPiMF_00637. Anti_sigma_F. 1 hit.
InterProiView protein in InterPro
IPR010194. Anti-sigma_F.
IPR003594. HATPase_C.
PfamiView protein in Pfam
PF13581. HATPase_c_2. 1 hit.
SMARTiView protein in SMART
SM00387. HATPase_c. 1 hit.
SUPFAMiSSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR01925. spIIAB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSP2AB_BACP2
AccessioniPrimary (citable) accession number: A8FET0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: February 15, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.