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A8FEK0 (TRPC_BACP2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Indole-3-glycerol phosphate synthase
Short name=IGPS
EC=4.1.1.48
Gene names
Name:trpC
Ordered Locus Names:BPUM_1997
OrganismBacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]
Taxonomic identifier315750 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134_B

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134_B

Sequence similarities

Belongs to the TrpC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 250250Indole-3-glycerol phosphate synthase HAMAP MF_00134_B
PRO_1000057871

Sequences

Sequence LengthMass (Da)Tools
A8FEK0 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: C1035227ECB6D9CE

FASTA25028,104
        10         20         30         40         50         60 
MLNQIIARKK EHIQTLQLPD DGHFERRSFK EALVNTHRSI GLIAEVKKAS PSKGIIQPNF 

        70         80         90        100        110        120 
DPLQTAKAYE KSNADCLSVL TDEPFFQGKN EYLSLIKKHI ARPILRKDFI IDSIQIEESR 

       130        140        150        160        170        180 
RIGADAILLI GEVLEPQQLH ELYIEAKEKG LDILVEVHAA ETLEQILNLF TPEIIGVNNR 

       190        200        210        220        230        240 
NLKTFNTTVE QTKEIAPLVP KDCLLVSESG IQTFDDLTFV KKHGASAVLV GESLMREPSQ 

       250 
EKAVQTLFGE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000813 Genomic DNA. Translation: ABV62667.1.
RefSeqYP_001487227.1. NC_009848.1.

3D structure databases

ProteinModelPortalA8FEK0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8FEK0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000063069; EBBACP00000061402; EBBACG00000063060.
GeneID5621266.
GenomeReviewsGene locus BPUM_1997 in contig CP000813_GR.
KEGGbpu:BPUM_1997.
PATRIC18967894. VBIBacPum16546_2043.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0134.
GeneTreeEBGT00050000001798.
HOGENOMHBG540956.
OMAFETDINT.
ProtClustDBPRK00278.

Enzyme and pathway databases

BioCycBPUM315750:BPUM_1997-MONOMER.

Family and domain databases

HAMAPMF_00134_B. IGPS_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01609.
PfamPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
PROSITEPS00614. IGPS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRPC_BACP2
AccessionPrimary (citable) accession number: A8FEK0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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