A8FEB8 (A8FEB8_BACP2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL ABV62585.1
EC=1.5.1.3 EMBL ABV62585.1

Gene names

Name:	dfrA EMBL ABV62585.1
Ordered Locus Names:	BPUM_1915

Organism

Bacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]

Taxonomic identifier

315750 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	161 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ABV62585.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8FEB8 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 9295ECB835294646	FASTA	161	18,458
	10 20 30 40 50 60 MISMIVATGK DRVIGQDNQM PWHLPADLAY FKKVTGGHTI VMGRKTYESI GRALPNRRNI 70 80 90 100 110 120 VLTTSSSFEA EGCEVVHSIA DILAIGKGET ELFIIGGSKL YEEMMPYADR LYITHIHHAF 130 140 150 160 EGDRYFPHYD ENKWTVVSRE KGHRDEKNPY NYEFVVYDKK G

References

[1]

"Paradoxical DNA repair and peroxide resistance gene conservation in Bacillus pumilus SAFR-032." Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D., Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H., Lee S., Nazareth L., Blyth P., Holder M., Buhay C. , Tirumalai M.R., Liu Y., Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P., Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D., Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F., Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K., Weinstock G.M. PLoS ONE 2:E928-E928(2007) [PubMed: 17895969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000813 Genomic DNA. Translation: ABV62585.1.
RefSeq	YP_001487145.1. NC_009848.1.
3D structure databases
ProteinModelPortal	A8FEB8.
SMR	A8FEB8. Positions 1-160.
ModBase	Search...
Protein-protein interaction databases
STRING	A8FEB8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000064452; EBBACP00000062785; EBBACG00000064443.
GeneID	5621183.
GenomeReviews	Gene locus BPUM_1915 in contig CP000813_GR.
KEGG	bpu:BPUM_1915.
PATRIC	18967728. VBIBacPum16546_1960.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0262.
GeneTree	EBGT00050000002709.
HOGENOM	HBG665708.
OMA	APNTFGY.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8FEB8_BACP2

Accession

Primary (citable) accession number: A8FEB8

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)