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A8FE33 (XYLA_BACP2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:BPUM_1829
OrganismBacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]
Taxonomic identifier315750 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_00455

Subunit structure

Homotetramer By similarity. HAMAP MF_00455

Subcellular location

Cytoplasm By similarity HAMAP MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

xylose isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 445445Xylose isomerase HAMAP MF_00455
PRO_1000060318

Sites

Active site1071 By similarity
Active site1101 By similarity
Metal binding2381Magnesium 1 By similarity
Metal binding2741Magnesium 1 By similarity
Metal binding2741Magnesium 2 By similarity
Metal binding2771Magnesium 2 By similarity
Metal binding3021Magnesium 1 By similarity
Metal binding3131Magnesium 2 By similarity
Metal binding3151Magnesium 2 By similarity
Metal binding3451Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
A8FE33 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 379343C01EDB2C87

FASTA44550,416
        10         20         30         40         50         60 
MANSNMKTLH SLEGIGKIQF EGKQSKNPLA FKSYNPSEVI GGKTMKDHLR FSVAYWHTLT 

        70         80         90        100        110        120 
ADGTDMFGTG TMQRAWDSYS GMDLAKARLE VAFQLFDLLD VPYFSFHDRD IAPEGDTLQE 

       130        140        150        160        170        180 
TNQHLDIILE RMKEYMRDSG VKLLWNTANM FKHPRFVHGA ATSCHADVFA YAAAQVKKGI 

       190        200        210        220        230        240 
ETAKELRAEN YVFWGGREGY DTLLNTDMKR ELDHMASFLH MAVDYAKEIG YTGQFLIEPK 

       250        260        270        280        290        300 
PKEPTTHQYD ADAATSIAFL KQYGLDTHFK LNIEANHATL AGHTFEHELR VARIHGLLGS 

       310        320        330        340        350        360 
VDANQGNTLL GWDTDEFPTD LYATTLAMYE ILQNGGLGTG GLNFDAKVRR ASFELEDILY 

       370        380        390        400        410        420 
AHIAGMDAFA KGLRVAHRLI EDRVFEDVIK HRYRSFSEGI GRDISEGKAN FHILEEYALK 

       430        440 
HPLIRNESGR EEQLKARLNQ YLLED

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000813 Genomic DNA. Translation: ABV62500.1.
RefSeqYP_001487060.1. NC_009848.1.

3D structure databases

ProteinModelPortalA8FE33.
SMRA8FE33. Positions 12-444.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8FE33.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000065935; EBBACP00000064268; EBBACG00000065926.
GeneID5621096.
GenomeReviewsGene locus BPUM_1829 in contig CP000813_GR.
KEGGbpu:BPUM_1829.
PATRIC18967542. VBIBacPum16546_1867.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2115.
GeneTreeEBGT00050000002648.
HOGENOMHBG297199.
OMALLGWDTD.
ProtClustDBPRK05474.

Enzyme and pathway databases

BioCycBPUM315750:BPUM_1829-MONOMER.

Family and domain databases

HAMAPMF_00455. Xylose_isom_A.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01805.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02630. Xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_BACP2
AccessionPrimary (citable) accession number: A8FE33
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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