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A8FD37 (A8FD37_BACP2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163
Gene names
Name:def EMBL ABV62154.1
Synonyms:def2 HAMAP MF_00163
Ordered Locus Names:BPUM_1471
OrganismBacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]
Taxonomic identifier315750 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length160 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1331 By similarity HAMAP MF_00163
Metal binding901Iron By similarity HAMAP MF_00163
Metal binding1321Iron By similarity HAMAP MF_00163
Metal binding1361Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A8FD37 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: ECEC78A106430C09

FASTA16017,678
        10         20         30         40         50         60 
MAVKPIVIHP AEVLEQKAES VDTFDKKLKK LLDDMYDTML ELDGVGLAAP QIGISQRIAV 

        70         80         90        100        110        120 
VDIGEESGRI DLVNPEVLEV KGSQTDIEGC LSFPSLYGTV ERPSYVKVKA FDKKGKPFTI 

       130        140        150        160 
EAEGFLARAL LHEIDHLDGI LFTSKIIQTY TEKELAEMEG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000813 Genomic DNA. Translation: ABV62154.1.
RefSeqYP_001486714.1. NC_009848.1.

3D structure databases

ProteinModelPortalA8FD37.
SMRA8FD37. Positions 1-150.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8FD37.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000063418; EBBACP00000061751; EBBACG00000063409.
GeneID5620738.
GenomeReviewsGene locus BPUM_1471 in contig CP000813_GR.
KEGGbpu:BPUM_1471.
PATRIC18966779. VBIBacPum16546_1486.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
GeneTreeEBGT00050000001175.
HOGENOMHBG665227.
OMAMINAHIE.
ProtClustDBPRK12846.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8FD37_BACP2
AccessionPrimary (citable) accession number: A8FD37
Entry history
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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