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Protein

Guanylate kinase

Gene

gmk

Organism
Bacillus pumilus (strain SAFR-032)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:BPUM_1467Imported
OrganismiBacillus pumilus (strain SAFR-032)Imported
Taxonomic identifieri315750 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001355 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi315750.BPUM_1467.

Structurei

3D structure databases

ProteinModelPortaliA8FD33.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 184Guanylate kinase-likeInterPro annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
HOGENOMiHOG000037639.
KOiK00942.
OMAiYGTLKSE.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A8FD33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKERGLLIVL SGPSGVGKGT VRQAIFSQED TKFEYSISVT TRKPREGERN
60 70 80 90 100
GVDYFFKSRE EFEHMIENKK LLEWAEYVGN YYGTPVDYVE QTLSEGKDVF
110 120 130 140 150
LEIEVQGALQ VREAFPEGLF IFLAPPSLSE LQNRIITRGT ESEELIRNRM
160 170 180 190 200
AAAKEEIEMM DAYDYVVEND DVELACERIK AIVLAEHLRR DRVAPRYKKM

LGVE
Length:204
Mass (Da):23,482
Last modified:November 13, 2007 - v1
Checksum:iA94011770A677444
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000813 Genomic DNA. Translation: ABV62150.1.
RefSeqiWP_003212381.1. NC_009848.4.

Genome annotation databases

EnsemblBacteriaiABV62150; ABV62150; BPUM_1467.
KEGGibpu:BPUM_1467.

Similar proteinsi

Entry informationi

Entry nameiA8FD33_BACP2
AccessioniPrimary (citable) accession number: A8FD33
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: September 27, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported