Skip Header

Contribute Send feedback
Read comments (?) or add your own

A8FCY1 (MURG_BACP2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
EC=2.4.1.227
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Gene names
Name:murG
Ordered Locus Names:BPUM_1415
OrganismBacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]
Taxonomic identifier315750 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP MF_00033

Catalytic activity

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00033

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00033

Subcellular location

Cell membrane; Peripheral membrane protein By similarity HAMAP MF_00033.

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 364364UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP MF_00033
PRO_1000057245

Sequences

Sequence LengthMass (Da)Tools
A8FCY1 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 4FC7866830F128EF

FASTA36440,281
        10         20         30         40         50         60 
MRIVISGGGT GGHIYPALAF IKEVKRLHPD VEFLYIGTEN GLEKKIVERE NIPFKAIEIS 

        70         80         90        100        110        120 
GFKRKLSFDN VKTVMRFLKG VQKSKSYLKE FKPDAVIGTG GYVCGPVVYA ASKLKIPTII 

       130        140        150        160        170        180 
HEQNSLPGIT NKFLARYVNK VAICFDEAKA HFPSEKVVFT GNPRASEVVS IKEGKSLKEF 

       190        200        210        220        230        240 
GLDENKKTVL IFGGSRGAAP INRAVIEMQE GLKAKNYQLL YITGEVHYEK VLNELKEKGL 

       250        260        270        280        290        300 
ASNMITKPFL HQMPEYLKSI DVIVARAGAT TIAEVTALGI PTIFIPSPYV TANHQEINAR 

       310        320        330        340        350        360 
SLEKHDAAIV LRESELTGDR LLHAIDEIAG NEEKLNQMSR LTKELGVPDA ATRLYNVLKE 


ITTT

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000813 Genomic DNA. Translation: ABV62098.1.
RefSeqYP_001486658.1. NC_009848.1.

3D structure databases

ProteinModelPortalA8FCY1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8FCY1.

Protein family/group databases

CAZyGT28. Glycosyltransferase Family 28.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000065241; EBBACP00000063574; EBBACG00000065232.
GeneID5620682.
GenomeReviewsGene locus BPUM_1415 in contig CP000813_GR.
KEGGbpu:BPUM_1415.
PATRIC18966665. VBIBacPum16546_1429.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0707.
GeneTreeEBGT00050000001194.
HOGENOMHBG617076.
OMAEDHQTKN.
ProtClustDBPRK00726.

Enzyme and pathway databases

BioCycBPUM315750:BPUM_1415-MONOMER.

Family and domain databases

HAMAPMF_00033. MurG.
[Tree]
InterProIPR006009. GlcNAc_MurG.
IPR004276. Glyco_trans_28.
IPR007235. Glyco_trans_28_C.
[Graphical view]
KOK02563.
PANTHERPTHR21015:SF22. PTHR21015:SF22. 1 hit.
PfamPF04101. Glyco_tran_28_C. 1 hit.
PF03033. Glyco_transf_28. 1 hit.
[Graphical view]
TIGRFAMsTIGR01133. MurG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURG_BACP2
AccessionPrimary (citable) accession number: A8FCY1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents