A8FAY9 (A8FAY9_BACP2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653

Gene names

Name:	yflG EMBL ABV61406.1
Ordered Locus Names:	BPUM_0719

Organism

Bacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]

Taxonomic identifier

315750 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	249 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653
Catalytic activity	Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653
Cofactor	Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653
Sequence similarities	Belongs to the peptidase M24A family. RuleBase RU003653

Ontologies

Keywords
Ligand	Cobalt RuleBase RU003653 Metal-binding RuleBase RU003653
Molecular function	Aminopeptidase RuleBase RU003653 EMBL ABV61406.1 Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloexopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8FAY9 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 94B6B07C16570878	FASTA	249	27,354
	10 20 30 40 50 60 MIVKHDHELE ALKKVGRIVA LAREEMKSQA KPGMSTKELD LIGKKILEEH GANSAPEKEY 70 80 90 100 110 120 DFPGTTCISV NDEVAHGIPS EKTILQEGDL INIDISAELD GYYSDTGISF VLGTGDARLE 130 140 150 160 170 180 ALCQCAEDAF LEGLKHAKAG KRQNQIGRAV YNTAKEQGFT VIKNLTGHGI GKSLHEAPNH 190 200 210 220 230 240 ILNYYDPFDN ALFKNGTVIA FEPFISTNAE SIYQADDGWT FKTPDKSLVA QIEHTIVITK DEPIILTKL

References

[1]

"Paradoxical DNA repair and peroxide resistance gene conservation in Bacillus pumilus SAFR-032." Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D., Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H., Lee S., Nazareth L., Blyth P., Holder M., Buhay C. , Tirumalai M.R., Liu Y., Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P., Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D., Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F., Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K., Weinstock G.M. PLoS ONE 2:E928-E928(2007) [PubMed: 17895969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000813 Genomic DNA. Translation: ABV61406.1.
RefSeq	YP_001485966.1. NC_009848.1.
3D structure databases
ProteinModelPortal	A8FAY9.
ModBase	Search...
Protein-protein interaction databases
STRING	A8FAY9.
Protein family/group databases
MEROPS	M24.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000064078; EBBACP00000062411; EBBACG00000064069.
GeneID	5619965.
GenomeReviews	Gene locus BPUM_0719 in contig CP000813_GR.
KEGG	bpu:BPUM_0719.
PATRIC	18965223. VBIBacPum16546_0729.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0024.
GeneTree	EBGT00070000031874.
HOGENOM	HBG299384.
OMA	VFTVEPF.
ProtClustDB	PRK12896.
Family and domain databases
InterPro	IPR001714. Pept_M24_MAP. IPR000994. Pept_M24_structural-domain. IPR002467. Pept_M24A_MAP1. [Graphical view]
Gene3D	G3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
KO	K01265.
Pfam	PF00557. Peptidase_M24. 1 hit. [Graphical view]
PRINTS	PR00599. MAPEPTIDASE.
SUPFAM	SSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMs	TIGR00500. Met_pdase_I. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8FAY9_BACP2

Accession

Primary (citable) accession number: A8FAY9

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)