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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

BPUM_0453

Organism
Bacillus pumilus (strain SAFR-032)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

BioCyciBPUM315750:G1G9U-500-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:BPUM_0453Imported
OrganismiBacillus pumilus (strain SAFR-032)Imported
Taxonomic identifieri315750 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001355 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi315750.BPUM_0453

Structurei

3D structure databases

ProteinModelPortaliA8FA81
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 77Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini101 – 138Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation

Phylogenomic databases

eggNOGiCOG0508 LUCA
HOGENOMiHOG000281566
KOiK00627
OMAiDNLCEVQ
OrthoDBiPOG091H0NG1

Family and domain databases

Gene3Di3.30.559.10, 1 hit
4.10.320.10, 1 hit
InterProiView protein in InterPro
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

A8FA81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVEVVMPKL GMSMKEGTVS VWNKEVGETV NKGESIASIN SEKIEMEIES
60 70 80 90 100
PAEGTILDIK VPEGEGVPPG TVICYIGEGN EQVEEKKEKG LPPKQKKERI
110 120 130 140 150
KISPVARKIA QSANLDIHTL VGTGPDGRIT KADVLRALPD EKEKQKQQNE
160 170 180 190 200
PTKHQPVSMM RKTIASRMME SLQTSAQLTI TMKADVTKLT NLQQQLNETA
210 220 230 240 250
IARYETKLTI TDFIAKAAIL SLLEHPAMNS QYHNGVVETF ENVHLGIAAA
260 270 280 290 300
LDNGLAVPVI QHAERLTLIE LAKSIKLYGK KAREGKLLHD EIRGSTFTIT
310 320 330 340 350
NLGAYGVEHF TPILNPPEAG ILGIGTMYDT PVYREDELCK GTILPLSLTF
360 370
DHRVLDGAPA SAFLSTVKAH LEEPISILL
Length:379
Mass (Da):41,453
Last modified:November 13, 2007 - v1
Checksum:i69EFF9278618F6B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000813 Genomic DNA Translation: ABV61148.1
RefSeqiWP_012009007.1, NC_009848.4

Genome annotation databases

EnsemblBacteriaiABV61148; ABV61148; BPUM_0453
KEGGibpu:BPUM_0453

Similar proteinsi

Entry informationi

Entry nameiA8FA81_BACP2
AccessioniPrimary (citable) accession number: A8FA81
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health