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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

BPUM_0453

Organism
Bacillus pumilus (strain SAFR-032)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:BPUM_0453Imported
OrganismiBacillus pumilus (strain SAFR-032)Imported
Taxonomic identifieri315750 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001355 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi315750.BPUM_0453.

Structurei

3D structure databases

ProteinModelPortaliA8FA81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 77Lipoyl-bindingInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation

Phylogenomic databases

eggNOGiCOG0508. LUCA.
HOGENOMiHOG000281566.
KOiK00627.
OMAiVHIGMAT.
OrthoDBiPOG091H0NG1.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8FA81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVEVVMPKL GMSMKEGTVS VWNKEVGETV NKGESIASIN SEKIEMEIES
60 70 80 90 100
PAEGTILDIK VPEGEGVPPG TVICYIGEGN EQVEEKKEKG LPPKQKKERI
110 120 130 140 150
KISPVARKIA QSANLDIHTL VGTGPDGRIT KADVLRALPD EKEKQKQQNE
160 170 180 190 200
PTKHQPVSMM RKTIASRMME SLQTSAQLTI TMKADVTKLT NLQQQLNETA
210 220 230 240 250
IARYETKLTI TDFIAKAAIL SLLEHPAMNS QYHNGVVETF ENVHLGIAAA
260 270 280 290 300
LDNGLAVPVI QHAERLTLIE LAKSIKLYGK KAREGKLLHD EIRGSTFTIT
310 320 330 340 350
NLGAYGVEHF TPILNPPEAG ILGIGTMYDT PVYREDELCK GTILPLSLTF
360 370
DHRVLDGAPA SAFLSTVKAH LEEPISILL
Length:379
Mass (Da):41,453
Last modified:November 13, 2007 - v1
Checksum:i69EFF9278618F6B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000813 Genomic DNA. Translation: ABV61148.1.
RefSeqiWP_012009007.1. NC_009848.4.

Genome annotation databases

KEGGibpu:BPUM_0453.
PATRICi18964655. VBIBacPum16546_0463.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000813 Genomic DNA. Translation: ABV61148.1.
RefSeqiWP_012009007.1. NC_009848.4.

3D structure databases

ProteinModelPortaliA8FA81.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315750.BPUM_0453.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGibpu:BPUM_0453.
PATRICi18964655. VBIBacPum16546_0463.

Phylogenomic databases

eggNOGiCOG0508. LUCA.
HOGENOMiHOG000281566.
KOiK00627.
OMAiVHIGMAT.
OrthoDBiPOG091H0NG1.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA8FA81_BACP2
AccessioniPrimary (citable) accession number: A8FA81
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: November 2, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.