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A8FA65 (A8FA65_BACP2) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase 1 HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr EMBL ABV61132.1
Synonyms:alr1 HAMAP MF_01201
Ordered Locus Names:BPUM_0437
OrganismBacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]
Taxonomic identifier315750 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length392 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 SAAS SAAS009006 RuleBase RU004247

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site411Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2691Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue411N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
A8FA65 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 0D07DAAEDCEC3C47

FASTA39243,775
        10         20         30         40         50         60 
MDTNAFYRDT WAEINLSAIK HNVSHMKDHI GQSVQLMAVV KANAYGHGDI EVASAALKAG 

        70         80         90        100        110        120 
ADILAVAFLD EAVSLRNKGI KAPILVLGAV PTEYVKVAVR YNVIMTAYSI DWLKDVINMM 

       130        140        150        160        170        180 
EGQMGQPIRF HLKIDSGMNR LGVKTIEQVN EVKKLVDEHS YLQLEGVFTH FATADEKDEA 

       190        200        210        220        230        240 
YFDRQVDTFQ TLLEPLHTDK LLIHCANSAA GLRFKDVLFN MVRFGISMYG LSPSEEIKDE 

       250        260        270        280        290        300 
LPFKLEEAMS LHTKLAHVKH IQKGESVSYG ATYTANQDTW IGTVPVGYAD GWIRKLAGTE 

       310        320        330        340        350        360 
VLVGGKRRKI TGRICMDQFM VELKDKLPVG EPVVLIGKQG EDMIQVDEIA KRLETINYEI 

       370        380        390 
TCSIGHRVPR VYIEDGKRVQ VRNPLLQGGP SF

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000813 Genomic DNA. Translation: ABV61132.1.
RefSeqYP_001485692.1. NC_009848.1.

3D structure databases

ProteinModelPortalA8FA65.
SMRA8FA65. Positions 4-385.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8FA65.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000066426; EBBACP00000064759; EBBACG00000066417.
GeneID5619664.
GenomeReviewsGene locus BPUM_0437 in contig CP000813_GR.
KEGGbpu:BPUM_0437.
PATRIC18964625. VBIBacPum16546_0448.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
GeneTreeEBGT00050000001615.
HOGENOMHBG712172.
OMAHYEIACN.
ProtClustDBCLSK886745.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8FA65_BACP2
AccessionPrimary (citable) accession number: A8FA65
Entry history
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info