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A8F9Z9 (MTLD_BACP2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase
EC=1.1.1.17
Gene names
Name:mtlD
Ordered Locus Names:BPUM_0371
OrganismBacillus pumilus (strain SAFR-032) [Complete proteome] [HAMAP]
Taxonomic identifier315750 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 373373Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_1000058530

Regions

Nucleotide binding3 – 1412NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
A8F9Z9 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: E608556334BA19D4

FASTA37340,725
        10         20         30         40         50         60 
MKALHFGAGN IGRGFIGSLL KTSGFELVFT DVNEAVINEL NARGEYTVEL AAPGQKQEIV 

        70         80         90        100        110        120 
GPVTAINSAQ DPAALTEAVA SADLITTAVG PAVLKIIASS IAEGLKQKNP DHIINIVACE 

       130        140        150        160        170        180 
NMIGGSSHLK EAVFSHLTEE EQKALSQTVG FPNAAVDRIV PIQHHEDILK VSVEPFFEWV 

       190        200        210        220        230        240 
IDETGFIGDV PQIDGATFVQ DLTPYIERKL FTVNTGHALA AYVGYQQGVQ TIKEAVDTPE 

       250        260        270        280        290        300 
IRQVVEGALH ETGSYLIDTY GFKKEEHDAY IQKIIKRFEN VFISDEVTRV ARSPLRKLGA 

       310        320        330        340        350        360 
DDRLIGPAKK MKQPVYLIKG IAAALAYDFA EDEEAVRLQK LRKEKGIEGV LEEVCGLTPT 

       370 
DDLYQAILKE TTR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000813 Genomic DNA. Translation: ABV61066.1.
RefSeqYP_001485626.1. NC_009848.1.

3D structure databases

ProteinModelPortalA8F9Z9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8F9Z9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000062950; EBBACP00000061283; EBBACG00000062941.
GeneID5619598.
GenomeReviewsGene locus BPUM_0371 in contig CP000813_GR.
KEGGbpu:BPUM_0371.
PATRIC18964483. VBIBacPum16546_0377.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0246.
GeneTreeEBGT00050000001216.
HOGENOMHBG568825.
OMAFANTAVD.
ProtClustDBPRK02318.

Enzyme and pathway databases

BioCycBPUM315750:BPUM_0371-MONOMER.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR023027. Mannitol_DH_CS.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_BACP2
AccessionPrimary (citable) accession number: A8F9Z9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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