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A8F8N1 (A8F8N1_THELT) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339

Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339
Ordered Locus Names:Tlet_1961 EMBL ABV34515.1
OrganismThermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / TMO) [Complete proteome] [HAMAP] EMBL ABV34515.1
Taxonomic identifier416591 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding21 – 255ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding155 – 1595ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding172 – 18817ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1281Proton acceptor By similarity HAMAP-Rule MF_00339
Metal binding1861Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_00339
Metal binding1881Magnesium By similarity HAMAP-Rule MF_00339
Binding site1631Substrate By similarity HAMAP-Rule MF_00339
Binding site2441Substrate By similarity HAMAP-Rule MF_00339
Binding site2501Substrate By similarity HAMAP-Rule MF_00339
Binding site2531Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
A8F8N1 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 052DB4FA317CFC68

FASTA31933,991
        10         20         30         40         50         60 
MKTIGVLTSG GDSPGMNAAI RAVVRFGVKN GLKVIGIQRG YCGMIDGAFK EMNFSDVAGI 

        70         80         90        100        110        120 
MERGGTILRT SRCGEFYTPE GRAKAAAKLK NAGIEGLVVI GGEGSLTGAK LLYEEHRIPV 

       130        140        150        160        170        180 
VGIPGTIDND IAQTDMCIGV DTCLNTVIDA IQKLKDTATS HERAFVVEVM GRESGYIALN 

       190        200        210        220        230        240 
AALATGSEAA IVPEVPVDFD KLAERLFEER KRGKINCIIV VAEGAGGAIQ VAKNLQDRIG 

       250        260        270        280        290        300 
YETRITILGH VQRGGSPTAF DRLLASRMGA EAVKALMNGE TCMMMALRMN RIEHVPIAEA 

       310 
LKSKKGLDMS LYELSLTLS 

« Hide

References

[1]"Complete sequence of Thermotoga lettingae TMO."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Bruce D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-301 / DSM 14385 / TMO.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000812 Genomic DNA. Translation: ABV34515.1.
RefSeqYP_001471579.1. NC_009828.1.

3D structure databases

ProteinModelPortalA8F8N1.
SMRA8F8N1. Positions 1-319.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING416591.Tlet_1961.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV34515; ABV34515; Tlet_1961.
GeneID5608249.
KEGGtle:Tlet_1961.
PATRIC23934645. VBITheLet125395_2051.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0205.
HOGENOMHOG000248870.
KOK00850.
OMAKMVHHDI.
OrthoDBEOG644ZRM.
ProtClustDBPRK03202.

Enzyme and pathway databases

BioCycTLET416591:GI64-2014-MONOMER.
UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012828. PFKA_ATP.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
TIGRFAMsTIGR02482. PFKA_ATP. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8F8N1_THELT
AccessionPrimary (citable) accession number: A8F8N1
Entry history
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)