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A8F720 (GLGA_THELT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:Tlet_1397
OrganismThermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / TMO) [Complete proteome] [HAMAP]
Taxonomic identifier416591 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Protein attributes

Sequence length486 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 486486Glycogen synthase HAMAP-Rule MF_00484
PRO_1000060435

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
A8F720 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: EAFFD3752DF00A30

FASTA48655,816
        10         20         30         40         50         60 
MRVAMVAYEV YPFAKVGGLA DVVGSLPKVI EKQGVKVTVF MPFHKIVSKN CEKLGLEIKE 

        70         80         90        100        110        120 
VARAISLPNL QTKEKFDLYK STVPATNVSV YFISNDYYFS ADNVYEGPDL AEQSIFFSNA 

       130        140        150        160        170        180 
AIEAMKYLSE TFDIVHAHDW QTGLVPVYLK TLYRTDPFFN RTATVFTIHN LGYQGVFNPG 

       190        200        210        220        230        240 
YMKFAGLPAY LFNIDGLEFY GQINFLKGGI LFSDIVTTVS PTYAQEIQTE QFGEKLDGVL 

       250        260        270        280        290        300 
RLRAEDLYGI LNGIDYSEYN PATDKRIYVN YDIDHIEKKK MNKSELQKEL NLQVRDDVPL 

       310        320        330        340        350        360 
IGMINRLVDQ KGLDLIEKIV DYMMMFDIQF VVLGTGDKKY EEFFKNIEKK YPQKISSNMK 

       370        380        390        400        410        420 
FDVDLAQKIY AASDMFLMPS RYEPCGLGQM YSLRYGTVPI VRYTGGLADS VKEYDPKTRD 

       430        440        450        460        470        480 
GNGFGFREYD TAHLLETVAK AVYFYKKEKD HWGKVVKNAM KTDVSWDRSA KQYLKIYQEA 


LRKKQF 

« Hide

References

[1]"Complete sequence of Thermotoga lettingae TMO."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Bruce D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-301 / DSM 14385 / TMO.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000812 Genomic DNA. Translation: ABV33954.1.
RefSeqYP_001471018.1. NC_009828.1.

3D structure databases

ProteinModelPortalA8F720.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING416591.Tlet_1397.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV33954; ABV33954; Tlet_1397.
GeneID5609230.
KEGGtle:Tlet_1397.
PATRIC23933429. VBITheLet125395_1463.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294940.
KOK00703.
OMADFSWERS.
OrthoDBEOG6JTC6Z.

Enzyme and pathway databases

BioCycTLET416591:GI64-1428-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_THELT
AccessionPrimary (citable) accession number: A8F720
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways