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A8F5X7 (COMB_THELT) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 2-phosphosulfolactate phosphatase

EC=3.1.3.71
Gene names
Name:comB
Ordered Locus Names:Tlet_0995
OrganismThermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / TMO) [Complete proteome] [HAMAP]
Taxonomic identifier416591 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490

Cofactor

Magnesium By similarity. HAMAP MF_00490

Sequence similarities

Belongs to the ComB family.

Ontologies

Keywords
   LigandMagnesium
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcoenzyme M biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular function2-phosphosulfolactate phosphatase activity

Inferred from electronic annotation. Source: EC

magnesium ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 224224Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490
PRO_1000081394

Sequences

Sequence LengthMass (Da)Tools
A8F5X7 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 3573ADD2C525D2AF

FASTA22425,015
        10         20         30         40         50         60 
MIDVLFLPEP VSQQHVCVVV DVLRATSTIV TALANGARCV VPVRKIAEAK KRKAENILIC 

        70         80         90        100        110        120 
GERKGIKPKG FDLGNSPIEY FTVKDKEVIL TTTNGTRAIS MINSQKLYAA CFLNLHAVIE 

       130        140        150        160        170        180 
QLRNHDHVTI VCSGQKGKIA YEDVLCAGAI VYELNDKLTD GARISRELWK QSRRKDLSKL 

       190        200        210        220 
LFESQHAQEL AEYGFSSDIT FCSQTDLYSI VPVFVEDRFI KQAP 

« Hide

References

[1]"Complete sequence of Thermotoga lettingae TMO."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Bruce D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-301 / DSM 14385 / TMO.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000812 Genomic DNA. Translation: ABV33561.1.
RefSeqYP_001470625.1. NC_009828.1.

3D structure databases

ProteinModelPortalA8F5X7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8F5X7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5608377.
GenomeReviewsGene locus Tlet_0995 in contig CP000812_GR.
KEGGtle:Tlet_0995.
PATRIC23932571. VBITheLet125395_1038.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG633644.
OMADFICSGY.
ProtClustDBPRK00886.

Enzyme and pathway databases

BioCycTLET416591:TLET_0995-MONOMER.

Family and domain databases

HAMAPMF_00490. ComB.
[Tree]
InterProIPR005238. 2-PSlactate_phosphatase.
IPR022995. Pase_ComB.
[Graphical view]
Gene3DG3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KOK05979.
PfamPF04029. 2-ph_phosp. 1 hit.
[Graphical view]
SUPFAMSSF142823. SSF142823. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOMB_THELT
AccessionPrimary (citable) accession number: A8F5X7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 13, 2007
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families