A8F4E8 (ACYP_THELT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	Tlet_0465

Organism

Thermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / TMO) [Complete proteome] [HAMAP]

Taxonomic identifier

416591 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	89 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein carbamoylation Inferred from electronic annotation. Source: InterPro
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC carboxyl- or carbamoyltransferase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 89	89	Acylphosphatase HAMAP MF_01450		PRO_0000326832
Regions
	Domain	3 – 89	87	Acylphosphatase-like
Sites
	Active site	18	1	By similarity
	Active site	36	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8F4E8 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: DA4FD5369C666CE8	FASTA	89	9,921
	10 20 30 40 50 60 MQALFIKISG RVHGVGFRYF TYKLANKMKI KGYVRNAEDG SVEIHAEAPE EILVEFLKAV 70 80 SIGPPMATVI SVKYERVAGQ NFTSFDIVP

References

[1]

"Complete sequence of Thermotoga lettingae TMO." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Bruce D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-301 / DSM 14385 / TMO.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000812 Genomic DNA. Translation: ABV33032.1.
RefSeq	YP_001470096.1. NC_009828.1.
3D structure databases
ProteinModelPortal	A8F4E8.
ModBase	Search...
Protein-protein interaction databases
STRING	A8F4E8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5608859.
GenomeReviews	Gene locus Tlet_0465 in contig CP000812_GR.
KEGG	tle:Tlet_0465.
PATRIC	23931447. VBITheLet125395_0493.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG750266.
OMA	YERVAGQ.
Enzyme and pathway databases
BioCyc	TLET416591:TLET_0465-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR004421. Carbamoyltransferase_HypF. [Graphical view]
KO	K01512.
PANTHER	PTHR10029:SF4. PTHR10029:SF4. 1 hit.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. False negative. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_THELT

Accession

Primary (citable) accession number: A8F4E8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program