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A8F2Z1 (SYGA_RICM5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase alpha subunit

EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS
Gene names
Name:glyQ
Ordered Locus Names:RMA_1337
OrganismRickettsia massiliae (strain Mtu5) [Complete proteome] [HAMAP]
Taxonomic identifier416276 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length288 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP-Rule MF_00254

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00254.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 288288Glycine--tRNA ligase alpha subunit HAMAP-Rule MF_00254
PRO_1000059056

Sequences

Sequence LengthMass (Da)Tools
A8F2Z1 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: CC7BA89CCC2DF1B6

FASTA28833,139
        10         20         30         40         50         60 
MKKLSFQQII LTLQNYWQDY GCAILQPYDA HVGAGTFHPA TVLRCLGTKP WSVAYVQPSR 

        70         80         90        100        110        120 
RPGDSRYGMH PNRMQHYYQF QVILKPSPDN IQELYLKSLE CLGIDLKIHD IRFVEDDWES 

       130        140        150        160        170        180 
PTLGAAGLGW EVWCNGMEVS QFTYMQQIGG IECRPVAGEI TYGLDRLALY IQGVDEVREL 

       190        200        210        220        230        240 
DWNGQVGEKA LKYGEVDFEA ERQFSKYNLE LADSEMLLRH FKDSEDQCER LIKANLPMPA 

       250        260        270        280 
YDECLKASHA FNQLNALGVI SVTERASYVL RVRHLARICC TKWLEMNK 

« Hide

References

[1]"Lateral gene transfer between obligate intracellular bacteria: evidence from the Rickettsia massiliae genome."
Blanc G., Ogata H., Robert C., Audic S., Claverie J.-M., Raoult D.
Genome Res. 17:1657-1664(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Mtu5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000683 Genomic DNA. Translation: ABV85277.1.
RefSeqYP_001499824.1. NC_009900.1.

3D structure databases

ProteinModelPortalA8F2Z1.
SMRA8F2Z1. Positions 4-288.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING416276.RMA_1337.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV85277; ABV85277; RMA_1337.
GeneID5665700.
KEGGrms:RMA_1337.
PATRIC17897390. VBIRicMas83254_1655.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0752.
HOGENOMHOG000264291.
KOK01878.
OMACVILQPY.
OrthoDBEOG661H9S.
ProtClustDBPRK09348.

Enzyme and pathway databases

BioCycRMAS416276:GJD3-1368-MONOMER.

Family and domain databases

HAMAPMF_00254. Gly_tRNA_synth_alpha.
InterProIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSPR01044. TRNASYNTHGA.
TIGRFAMsTIGR00388. glyQ. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGA_RICM5
AccessionPrimary (citable) accession number: A8F2Z1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries