A8F2Q2 (ACP_RICM5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acyl carrier protein
Short name=ACP

Gene names

Name:	acpP
Ordered Locus Names:	RMA_1205

Organism

Rickettsia massiliae (strain Mtu5) [Complete proteome] [HAMAP]

Taxonomic identifier

416276 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	86 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Carrier of the growing fatty acid chain in fatty acid biosynthesis By similarity. HAMAP MF_01217
Pathway	Lipid metabolism; fatty acid biosynthesis. HAMAP MF_01217
Subcellular location	Cytoplasm By similarity HAMAP MF_01217.
Post-translational modification	4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group By similarity. HAMAP MF_01217
Sequence similarities	Contains 1 acyl carrier domain.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Ligand	Phosphopantetheine
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 86	86	Acyl carrier protein HAMAP MF_01217		PRO_1000066681
Amino acid modifications
	Modified residue	45	1	O-(pantetheine 4'-phosphoryl)serine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8F2Q2 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 907E164E5FEC8E4F	FASTA	86	9,903
	10 20 30 40 50 60 MEFKIMSTTD KIEQKVIEMV AEKLNKDKSI ITTDSRFIED LKADSLDTVE LMMAIEVEYG 70 80 IDIPDDEATK IKTVSDVIKY IKERQS

References

[1]

"Lateral gene transfer between obligate intracellular bacteria: evidence from the Rickettsia massiliae genome." Blanc G., Ogata H., Robert C., Audic S., Claverie J.-M., Raoult D. Genome Res. 17:1657-1664(2007) [PubMed: 17916642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Mtu5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000683 Genomic DNA. Translation: ABV85188.1.
RefSeq	YP_001499735.1. NC_009900.1.
3D structure databases
ProteinModelPortal	A8F2Q2.
ModBase	Search...
Protein-protein interaction databases
STRING	A8F2Q2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5665961.
GenomeReviews	Gene locus RMA_1205 in contig CP000683_GR.
KEGG	rms:RMA_1205.
PATRIC	17897053. VBIRicMas83254_1490.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0236.
HOGENOM	HBG755218.
OMA	QIIMGIE.
ProtClustDB	PRK00982.
Enzyme and pathway databases
BioCyc	RMAS416276:RMA_1205-MONOMER.
Family and domain databases
HAMAP	MF_01217. Acyl_carrier. [Tree]
InterPro	IPR003231. Acyl_carrier. IPR009081. Acyl_carrier_prot-like. IPR006163. Phsphopanteth-bd. [Graphical view]
Gene3D	G3DSA:1.10.1200.10. ACP_like. 1 hit.
KO	K02078.
Pfam	PF00550. PP-binding. 1 hit. [Graphical view]
ProDom	PD000887. PD000887. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF47336. ACP_like. 1 hit.
TIGRFAMs	TIGR00517. Acyl_carrier. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00012. PHOSPHOPANTETHEINE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACP_RICM5

Accession

Primary (citable) accession number: A8F2Q2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program