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A8F0W4 (A8F0W4_RICM5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163
Gene names
Name:def1 EMBL ABV84550.1
Synonyms:def2 HAMAP MF_00163
Ordered Locus Names:RMA_0279
OrganismRickettsia massiliae (strain Mtu5) [Complete proteome] [HAMAP] EMBL ABV84550.1
Taxonomic identifier416276 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length176 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1431 By similarity HAMAP MF_00163
Metal binding1001Iron By similarity HAMAP MF_00163
Metal binding1421Iron By similarity HAMAP MF_00163
Metal binding1461Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A8F0W4 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 882F0B66C1CAAF61

FASTA17620,338
        10         20         30         40         50         60 
MMSILPIVTA PDERLKQKSQ PVLEFTDQTR KFMDDMLKTM YHKDGAGLAA VQVGVLKRIL 

        70         80         90        100        110        120 
VIDIKDHDSV ARPKDFYPLF IVNPEIIEKS EELVTANEGC ISLPEQRIEV ARPESIKIRC 

       130        140        150        160        170 
LDYHGKSQEL QANDWLARVI QHEYDHLEGK LMIDYLSNLK RDVVLRKLKK LKNNIV

« Hide

References

[1]"Lateral gene transfer between obligate intracellular bacteria: evidence from the Rickettsia massiliae genome."
Blanc G., Ogata H., Robert C., Audic S., Claverie J.-M., Raoult D.
Genome Res. 17:1657-1664(2007) [PubMed: 17916642] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000683 Genomic DNA. Translation: ABV84550.1.
RefSeqYP_001499097.1. NC_009900.1.

3D structure databases

ProteinModelPortalA8F0W4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8F0W4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5665692.
GenomeReviewsGene locus RMA_0279 in contig CP000683_GR.
KEGGrms:RMA_0279.
PATRIC17894742. VBIRicMas83254_0362.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAETMIASE.
ProtClustDBPRK00150.

Enzyme and pathway databases

BioCycRMAS416276:RMA_0279-MONOMER.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8F0W4_RICM5
AccessionPrimary (citable) accession number: A8F0W4
Entry history
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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