A8EXD1 (DGTL1_RICCK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxyguanosinetriphosphate triphosphohydrolase-like protein

Gene names

Ordered Locus Names:

A1E_00305

Organism

Rickettsia canadensis (strain McKiel) [Complete proteome] [HAMAP]

Taxonomic identifier

293613 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dGTPase family. Type 2 subfamily.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	GTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	dGTPase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 376	376	Deoxyguanosinetriphosphate triphosphohydrolase-like protein HAMAP MF_01212		PRO_1000066439

Sequences

	Sequence		Length	Mass (Da)
	A8EXD1 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 21C1742B7CAD240A	FASTA	376	43,328
	10 20 30 40 50 60 MLASYASDPL KSRGRLYKEI PNTYRNEFER DRDRIIHTNA FRRLQYKTQV FINHEGDHYR 70 80 90 100 110 120 NRLTHSLEVS AVARSVANTL NLSSDLAETI ALAHDLGHTP FGHAGERALN ACMRDYNGFS 130 140 150 160 170 180 HNAQSLKILT LLEKRYAAYN GVNLTWEVLE GIVKHNGPIT CEINEYIAEY NKQNDLELDT 190 200 210 220 230 240 YASAEAQIAA LADDISYISH DLEDSIGAKI IDFNSLAELK YIDQYVFALK SKFKNISSSC 250 260 270 280 290 300 LIYEVVRKLM HELITDLLWQ TKENLNKEKI TDIDEIRNLN YQLVDFTANT NERIKETKKF 310 320 330 340 350 360 LHERVYKSNK ITAISLKCTK IVQGLFKVYM DDINLLPVNW KMLIDSNEIY SKARVIADYI 370 AGMTDRFAIQ AYNQLC

References

[1]	"Complete genome sequence of Rickettsia canadensis." Madan A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Dasch G., Eremeeva M. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: McKiel.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000409 Genomic DNA. Translation: ABV73014.1.
RefSeq	YP_001491799.1. NC_009879.1.
3D structure databases
ProteinModelPortal	A8EXD1.
ModBase	Search...
Protein-protein interaction databases
STRING	A8EXD1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5626876.
GenomeReviews	Gene locus A1E_00305 in contig CP000409_GR.
KEGG	rcm:A1E_00305.
PATRIC	17884681. VBIRicCan89738_0071.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0232.
HOGENOM	HBG500914.
OMA	ITRFVED.
ProtClustDB	PRK01286.
Enzyme and pathway databases
BioCyc	RCAN293613:A1E_00305-MONOMER.
Family and domain databases
HAMAP	MF_01212. dGTPase_type2. [Tree]
InterPro	IPR006261. dGTP_triP_hydro. IPR023293. dGTP_triP_hydro_central. IPR023023. dGTP_triP_hydro_type2. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. [Graphical view]
Gene3D	G3DSA:1.10.3410.10. G3DSA:1.10.3410.10. 1 hit. G3DSA:1.10.3210.10. HD. 1 hit.
KO	K01129.
Pfam	PF01966. HD. 1 hit. [Graphical view]
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01353. DGTP_triPase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DGTL1_RICCK

Accession

Primary (citable) accession number: A8EXD1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program