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A8EX66 (GLSA_ARCB4) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutaminase
EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:Abu_2331
OrganismArcobacter butzleri (strain RM4018) [Complete proteome] [HAMAP]
Taxonomic identifier367737 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Arcobacter ›

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305Glutaminase HAMAP-Rule MF_00313
PRO_0000336023

Sites

Binding site631Substrate By similarity
Binding site1131Substrate By similarity
Binding site1581Substrate By similarity
Binding site1651Substrate By similarity
Binding site1891Substrate By similarity
Binding site2411Substrate By similarity
Binding site2591Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A8EX66 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: EB8B73BD48B03309

FASTA30533,897
        10         20         30         40         50         60 
MNYQTILEEI EKEIQALFVE GKVASYIPAL ANVNPNQFSM AIKMFDGQTF GVGEIDKKFS 

        70         80         90        100        110        120 
IQSISKVFTF TLALNYYGKE LYKRVSHEPS GNPFNSLVQL EYENGIPRNP FINAGAIVTA 

       130        140        150        160        170        180 
DTLVSIYKND TFNQILDFIK MVSNDKTIDF NEEIFHSELE HGFRNYALIN MIKSFGNIHN 

       190        200        210        220        230        240 
DIDEVIKTYF KQCSIMMSPS QLASSMLFLA NHGINPITNE RILTESKAKR ISSLMLTCGH 

       250        260        270        280        290        300 
YDASGDFAYK VGLPGKSGVG GGIVAIVPKK MAICVYSPKL NTQGNSLIGT KALELFTTKT 


GLSIF

« Hide

References

[1]"The complete genome sequence and analysis of the Epsilonproteobacterium Arcobacter butzleri."
Miller W.G., Parker C.T., Rubenfield M., Mendz G.L., Woesten M.M.S.M., Ussery D.W., Stolz J.F., Binnewies T.T., Hallin P.F., Wang G., Malek J.A., Rogosin A., Stanker L.H., Mandrell R.E.
PLoS ONE 2:E1358-E1358(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RM4018.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000361 Genomic DNA. Translation: ABV68539.1.
RefSeqYP_001491209.1. NC_009850.1.

3D structure databases

ProteinModelPortalA8EX66.
ModBaseSearch...

Protein-protein interaction databases

STRING367737.Abu_2331.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV68539; ABV68539; Abu_2331.
GeneID5625148.
KEGGabu:Abu_2331.
PATRIC20966028. VBIArcBut20197_2271.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAEPSGNPF.
ProtClustDBCLSK2795227.

Enzyme and pathway databases

BioCycABUT367737:GHWO-2329-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. PBP_transp_fold. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_ARCB4
AccessionPrimary (citable) accession number: A8EX66
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 13, 2007
Last modified: May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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