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A8EX66

- GLSA_ARCB4

UniProt

A8EX66 - GLSA_ARCB4

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Protein

Glutaminase

Gene
glsA, Abu_2331
Organism
Arcobacter butzleri (strain RM4018)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631Substrate By similarity
Binding sitei113 – 1131Substrate By similarity
Binding sitei158 – 1581Substrate By similarity
Binding sitei165 – 1651Substrate By similarity
Binding sitei189 – 1891Substrate By similarity
Binding sitei241 – 2411Substrate By similarity
Binding sitei259 – 2591Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciABUT367737:GHWO-2329-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Abu_2331
OrganismiArcobacter butzleri (strain RM4018)
Taxonomic identifieri367737 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeArcobacter
ProteomesiUP000001136: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 305305GlutaminaseUniRule annotationPRO_0000336023Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi367737.Abu_2331.

Structurei

3D structure databases

ProteinModelPortaliA8EX66.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQRARRIN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A8EX66-1 [UniParc]FASTAAdd to Basket

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MNYQTILEEI EKEIQALFVE GKVASYIPAL ANVNPNQFSM AIKMFDGQTF    50
GVGEIDKKFS IQSISKVFTF TLALNYYGKE LYKRVSHEPS GNPFNSLVQL 100
EYENGIPRNP FINAGAIVTA DTLVSIYKND TFNQILDFIK MVSNDKTIDF 150
NEEIFHSELE HGFRNYALIN MIKSFGNIHN DIDEVIKTYF KQCSIMMSPS 200
QLASSMLFLA NHGINPITNE RILTESKAKR ISSLMLTCGH YDASGDFAYK 250
VGLPGKSGVG GGIVAIVPKK MAICVYSPKL NTQGNSLIGT KALELFTTKT 300
GLSIF 305
Length:305
Mass (Da):33,897
Last modified:November 13, 2007 - v1
Checksum:iEB8B73BD48B03309
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000361 Genomic DNA. Translation: ABV68539.1.
RefSeqiWP_012148151.1. NC_009850.1.
YP_001491209.1. NC_009850.1.

Genome annotation databases

EnsemblBacteriaiABV68539; ABV68539; Abu_2331.
GeneIDi5625148.
KEGGiabu:Abu_2331.
PATRICi20966028. VBIArcBut20197_2271.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000361 Genomic DNA. Translation: ABV68539.1 .
RefSeqi WP_012148151.1. NC_009850.1.
YP_001491209.1. NC_009850.1.

3D structure databases

ProteinModelPortali A8EX66.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 367737.Abu_2331.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABV68539 ; ABV68539 ; Abu_2331 .
GeneIDi 5625148.
KEGGi abu:Abu_2331.
PATRICi 20966028. VBIArcBut20197_2271.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QRARRIN.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci ABUT367737:GHWO-2329-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RM4018.

Entry informationi

Entry nameiGLSA_ARCB4
AccessioniPrimary (citable) accession number: A8EX66
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 13, 2007
Last modified: September 3, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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