A8EX03 (SURE_ARCB4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	Abu_2263

Organism

Arcobacter butzleri (strain RM4018) [Complete proteome] [HAMAP]

Taxonomic identifier

367737 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Arcobacter

Protein attributes

Sequence length	262 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 262	262	5'-nucleotidase surE HAMAP MF_00060		PRO_0000335254
Sites
	Metal binding	9	1	Divalent metal cation By similarity
	Metal binding	10	1	Divalent metal cation By similarity
	Metal binding	40	1	Divalent metal cation By similarity
	Metal binding	95	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8EX03 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 3D21C17AC9233B05	FASTA	262	29,197
	10 20 30 40 50 60 MKHILLTNDD GYDSVGLKAL IDALSPIAKI TVVAPANNKS ACGHSLTLDK PLRLISIKDD 70 80 90 100 110 120 FYKIDDGSPT DCIFLSLGNL FKEGFKPDLV ISGINIGANM GEDITYSGTA SAAMEAVIHK 130 140 150 160 170 180 IPAIAISQVC QNRCQDIQNG WEFELAKDTI VKLATRILNN SFPLDERKFL NVNIPPIKPN 190 200 210 220 230 240 ECKGMKITKA GFREYGTDSD RHINPRGEEY YWIGLHPLIW KASEDQSCDF EAIKENYVSI 250 260 SPIKLDMTSY DDLKNLENWL NN

References

[1]

"The complete genome sequence and analysis of the Epsilonproteobacterium Arcobacter butzleri." Miller W.G., Parker C.T., Rubenfield M., Mendz G.L., Woesten M.M.S.M., Ussery D.W., Stolz J.F., Binnewies T.T., Hallin P.F., Wang G., Malek J.A., Rogosin A., Stanker L.H., Mandrell R.E. PLoS ONE 2:E1358-E1358(2007) [PubMed: 18159241] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RM4018.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000361 Genomic DNA. Translation: ABV68476.1.
RefSeq	YP_001491146.1. NC_009850.1.
3D structure databases
ProteinModelPortal	A8EX03.
ModBase	Search...
Protein-protein interaction databases
STRING	A8EX03.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5624649.
GenomeReviews	Gene locus Abu_2263 in contig CP000361_GR.
KEGG	abu:Abu_2263.
PATRIC	20965892. VBIArcBut20197_2207.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	DCVKMGI.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	ABUT367737:ABU_2263-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_ARCB4

Accession

Primary (citable) accession number: A8EX03

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program