Reviewed, UniProtKB/Swiss-Prot A8EWM4 (PGK_ARCB4)

Names and origin

Protein names

Recommended name:
    Phosphoglycerate kinase
    EC=2.7.2.3

Gene names

Name:	pgk
Ordered Locus Names:	Abu_2133

Organism

Arcobacter butzleri (strain RM4018) [Complete proteome] [HAMAP]

Taxonomic identifier

367737 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Arcobacter

Protein attributes

Sequence length	400 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 400	400	Phosphoglycerate kinase HAMAP MF_00145		PRO_1000057960
Regions
	Nucleotide binding	353 – 356	4	ATP By similarity
	Region	21 – 23	3	Substrate binding By similarity
	Region	60 – 63	4	Substrate binding By similarity
Sites
	Binding site	37	1	Substrate By similarity
	Binding site	119	1	Substrate By similarity
	Binding site	152	1	Substrate By similarity
	Binding site	205	1	ATP By similarity
	Binding site	296	1	ATP; via carbonyl oxygen By similarity
	Binding site	327	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8EWM4-1 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 7354C02EB11DF199	FASTA	400	43,845
	10 20 30 40 50 60 MKLQEIKNID ITGKKVFIRC DFNVPMDEYN NITDDRRIRS ALNTIRYCID HDCSVILSSH 70 80 90 100 110 120 FGRPKGGFEE KYSLLPIAKR LHILLKQDIK MAPGVICDET LQMAKELKAG EILLLENMRF 130 140 150 160 170 180 EAGETKNDEE LSKKLASMAE IYINDAFGVS HRAHASVEGI SKYFDIEHKA AGFLMAKEIK 190 200 210 220 230 240 FFHHIIHNPK RPFIAIVGGS KVSGKLEALY NLIPKVDKII IGGGMAFTFL KARGHEIGNS 250 260 270 280 290 300 LVEDDLIPEA LKIMEEAKSK GVKLYLPVDV VAAEAFDAEA IAKIATIQEM PKGWMGLDIG 310 320 330 340 350 360 PASALLFSEA LSDANTILWN GPMGVYEMDR FAKGSTKISH AVANSYATTV VGGGDTADLV 370 380 390 400 RVTGDEDDMT FISTGGGASL ELIEGKVLPG VKALVIEEND

References

[1]

"The complete genome sequence and analysis of the Epsilonproteobacterium Arcobacter butzleri." Miller W.G., Parker C.T., Rubenfield M., Mendz G.L., Woesten M.M.S.M., Ussery D.W., Stolz J.F., Binnewies T.T., Hallin P.F., Wang G., Malek J.A., Rogosin A., Stanker L.H., Mandrell R.E. PLoS ONE 2:E1358-E1358(2007) [PubMed: 18159241] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000361 Genomic DNA. Translation: ABV68347.1.
RefSeq	YP_001491017.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A8EWM4.
Genome annotation databases
GeneID	5624610.
GenomeReviews	Gene locus Abu_2133 in contig CP000361_GR.
KEGG	abu:Abu_2133.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CLENTRF.
Family and domain databases
HAMAP	MF_00145. [Tree]
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
Gene3D	G3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit. G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
PANTHER	PTHR11406. PGK. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PRINTS	PR00477. PHGLYCKINASE.
PROSITE	PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGK_ARCB4

Accession

Primary (citable) accession number: A8EWM4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	November 3, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)