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A8EWM4

- PGK_ARCB4

UniProt

A8EWM4 - PGK_ARCB4

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Protein
Phosphoglycerate kinase
Gene
pgk, Abu_2133
Organism
Arcobacter butzleri (strain RM4018)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371Substrate By similarity
Binding sitei119 – 1191Substrate By similarity
Binding sitei152 – 1521Substrate By similarity
Binding sitei205 – 2051ATP By similarity
Binding sitei296 – 2961ATP; via carbonyl oxygen By similarity
Binding sitei327 – 3271ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi353 – 3564ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciABUT367737:GHWO-2131-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:Abu_2133
OrganismiArcobacter butzleri (strain RM4018)
Taxonomic identifieri367737 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeArcobacter
ProteomesiUP000001136: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Phosphoglycerate kinaseUniRule annotation
PRO_1000057960Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi367737.Abu_2133.

Structurei

3D structure databases

ProteinModelPortaliA8EWM4.
SMRiA8EWM4. Positions 5-396.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni60 – 634Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiMSIRYID.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8EWM4-1 [UniParc]FASTAAdd to Basket

« Hide

MKLQEIKNID ITGKKVFIRC DFNVPMDEYN NITDDRRIRS ALNTIRYCID    50
HDCSVILSSH FGRPKGGFEE KYSLLPIAKR LHILLKQDIK MAPGVICDET 100
LQMAKELKAG EILLLENMRF EAGETKNDEE LSKKLASMAE IYINDAFGVS 150
HRAHASVEGI SKYFDIEHKA AGFLMAKEIK FFHHIIHNPK RPFIAIVGGS 200
KVSGKLEALY NLIPKVDKII IGGGMAFTFL KARGHEIGNS LVEDDLIPEA 250
LKIMEEAKSK GVKLYLPVDV VAAEAFDAEA IAKIATIQEM PKGWMGLDIG 300
PASALLFSEA LSDANTILWN GPMGVYEMDR FAKGSTKISH AVANSYATTV 350
VGGGDTADLV RVTGDEDDMT FISTGGGASL ELIEGKVLPG VKALVIEEND 400
Length:400
Mass (Da):43,845
Last modified:November 13, 2007 - v1
Checksum:i7354C02EB11DF199
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000361 Genomic DNA. Translation: ABV68347.1.
RefSeqiWP_012147996.1. NC_009850.1.
YP_001491017.1. NC_009850.1.

Genome annotation databases

EnsemblBacteriaiABV68347; ABV68347; Abu_2133.
GeneIDi5624610.
KEGGiabu:Abu_2133.
PATRICi20965630. VBIArcBut20197_2076.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000361 Genomic DNA. Translation: ABV68347.1 .
RefSeqi WP_012147996.1. NC_009850.1.
YP_001491017.1. NC_009850.1.

3D structure databases

ProteinModelPortali A8EWM4.
SMRi A8EWM4. Positions 5-396.
ModBasei Search...

Protein-protein interaction databases

STRINGi 367737.Abu_2133.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABV68347 ; ABV68347 ; Abu_2133 .
GeneIDi 5624610.
KEGGi abu:Abu_2133.
PATRICi 20965630. VBIArcBut20197_2076.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi MSIRYID.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci ABUT367737:GHWO-2131-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RM4018.

Entry informationi

Entry nameiPGK_ARCB4
AccessioniPrimary (citable) accession number: A8EWM4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: September 3, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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