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Protein

Aspartate ammonia-lyase

Gene

aspA

Organism
Arcobacter butzleri (strain RM4018)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate = fumarate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

BioCyciABUT367737:GHWO-1579-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate ammonia-lyaseUniRule annotation (EC:4.3.1.1UniRule annotation)
Short name:
AspartaseUniRule annotation
Gene namesi
Name:aspAImported
Ordered Locus Names:Abu_1581Imported
OrganismiArcobacter butzleri (strain RM4018)Imported
Taxonomic identifieri367737 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeArcobacter
Proteomesi
  • UP000001136 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi367737.Abu_1581.

Structurei

3D structure databases

ProteinModelPortaliA8EV56.
SMRiA8EV56. Positions 1-457.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 344332Lyase_1InterPro annotationAdd
BLAST
Domaini410 – 46253FumaraseC_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.
HOGENOMiHOG000061737.
KOiK01744.
OMAiEICENYV.
OrthoDBiPOG091H01XG.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8EV56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKQYRIEKD FLGEKEIELD KYYGVQTLRA KENFNITTLG ISIFPTFIIS
60 70 80 90 100
LAKVKKACAL TNYELGDLTD IQKNAIVEAC DRIIAGEFHD QFIVDPIQGG
110 120 130 140 150
AGTSTNMNAN EVIANVALEI LGYPKSSYDI IHPNNHINMS QSTNDVYPTA
160 170 180 190 200
IKIALYELIF KLQDSLKILR DSFHDKAVEF KDILKMGRTQ LQDAVPMTLG
210 220 230 240 250
QEFKTYATMI DDDIFRLSRA QDMLKEVNLG ATAIGTGINT KPEYQELVIK
260 270 280 290 300
NLRIVTGTEY YKANDMIEAT QDTGSFVQIS GRFKSIAIKV SKICNDLRLL
310 320 330 340 350
SSGPRAGLNE INLPPMQPGS SIMPGKVNPV MPEVVNQVAF EVIGADTTIA
360 370 380 390 400
IASEHGQLQL NVFEPIIAYK LFISINMMRR AFESLAEKCI KGITANPEIC
410 420 430 440 450
MNNVLNSATL VTSLSPIIGY EKSSAVAKEA LRTGKRVYDI LLEQNLFTKE
460
ELDELLQPKN MVQNYDKI
Length:468
Mass (Da):52,202
Last modified:November 13, 2007 - v1
Checksum:iD68A135F9A09D01F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000361 Genomic DNA. Translation: ABV67829.1.
RefSeqiWP_012147578.1. NC_009850.1.

Genome annotation databases

EnsemblBacteriaiABV67829; ABV67829; Abu_1581.
GeneIDi24305647.
KEGGiabu:Abu_1581.
PATRICi20964524. VBIArcBut20197_1553.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000361 Genomic DNA. Translation: ABV67829.1.
RefSeqiWP_012147578.1. NC_009850.1.

3D structure databases

ProteinModelPortaliA8EV56.
SMRiA8EV56. Positions 1-457.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi367737.Abu_1581.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV67829; ABV67829; Abu_1581.
GeneIDi24305647.
KEGGiabu:Abu_1581.
PATRICi20964524. VBIArcBut20197_1553.

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.
HOGENOMiHOG000061737.
KOiK01744.
OMAiEICENYV.
OrthoDBiPOG091H01XG.

Enzyme and pathway databases

BioCyciABUT367737:GHWO-1579-MONOMER.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA8EV56_ARCB4
AccessioniPrimary (citable) accession number: A8EV56
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.