A8EU11 (A8EU11_ARCB4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
GTPase Der HAMAP-Rule MF_00195 RuleBase RU004481

Alternative name(s):
GTP-binding protein EngA HAMAP-Rule MF_00195

Gene names

Name:	engA EMBL ABV67435.1
Synonyms:	der HAMAP-Rule MF_00195
Ordered Locus Names:	Abu_1175 EMBL ABV67435.1

Organism

Arcobacter butzleri (strain RM4018) [Complete proteome] [HAMAP] EMBL ABV67435.1

Taxonomic identifier

367737 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Arcobacter › Arcobacter butzleri

Protein attributes

Sequence length	485 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	GTPase that plays an essential role in the late steps of ribosome biogenesis By similarity. HAMAP-Rule MF_00195 RuleBase RU004481
Subunit structure	Associates with the 50S ribosomal subunit By similarity. HAMAP-Rule MF_00195
Sequence similarities	Belongs to the Era/MnmE GTP-binding protein family. Der subfamily. HAMAP-Rule MF_00195 RuleBase RU004481 Contains 1 KH-like domain. HAMAP-Rule MF_00195 SAAS SAAS016484 Contains 2 G (guanine nucleotide-binding) domains. HAMAP-Rule MF_00195 SAAS SAAS016484

Ontologies

Keywords
Biological process	Ribosome biogenesis HAMAP-Rule MF_00195 SAAS SAAS016484
Domain	Repeat HAMAP-Rule MF_00195 RuleBase RU004481 SAAS SAAS016484
Ligand	GTP-binding HAMAP-Rule MF_00195 SAAS SAAS016484 RuleBase RU004481 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ribosome biogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Domain	7 – 122	116	G 1 By similarity HAMAP-Rule MF_00195
	Domain	220 – 336	117	G 2 By similarity HAMAP-Rule MF_00195
	Domain	389 – 475	87	KH-like By similarity HAMAP-Rule MF_00195
	Nucleotide binding	12 – 19	8	GTP 1 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	59 – 63	5	GTP 1 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	121 – 124	4	GTP 1 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	224 – 231	8	GTP 2 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	271 – 275	5	GTP 2 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	335 – 338	4	GTP 2 By similarity HAMAP-Rule MF_00195

Sequences

	Sequence		Length	Mass (Da)
	A8EU11 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: AA1C00AE71C22793	FASTA	485	55,514
	10 20 30 40 50 60 MDNTLKKIAL IGQPNVGKSS LFNRIANKRI AIVSDMAGTT RDIRKHEIEI LDRVGLLVDT 70 80 90 100 110 120 GGIDDTNDAI FSNVKRKAIE TAKEADIILF MVDGKNIPDD KDKELFYELQ RLGKELALVV 130 140 150 160 170 180 NKIDNDKELE RLWEFFEFGI GDENLFGISV SHNRGTKLLF EWIYKHLPVN LETVAREEAE 190 200 210 220 230 240 ALKKQREENF EFDDEEDFSS EGIESLEEET VEIDDSKINV AIIGRVNVGK SSVLNAIVGA 250 260 270 280 290 300 ERSVVSPIAG TTIDPVDESF EYKEKQITFV DTAGLRRRGS IEGIEKYALM RTKEMLEKAN 310 320 330 340 350 360 MALVVLDASR ELTDLDEKIA GLVDEYGLGT IIVLNKWDEN MDTFQKIEEE IRRRFRFLSY 370 380 390 400 410 420 APIIAVSAKT GRSIERLKDK IIEIFDNYTQ RIPTSQLNKV IEEAVIRHSL PSPNGAYLRI 430 440 450 460 470 480 YYTTQFSTRP PKIALVMNKP NLLHYSYKRY LVNFLRERFN FEGTPIHVIA RGKNDKMGDE EYLER

References

[1]

"The Complete Genome Sequence and Analysis of the Epsilonproteobacterium Arcobacter butzleri." Miller W.G., Parker C.T., Rubenfield M., Mendz G.L., Wosten M.M., Ussery D.W., Stolz J.F., Binnewies T.T., Hallin P.F., Wang G., Malek J.A., Rogosin A., Stanker L.H., Mandrell R.E. PLoS ONE 2:E1358-E1358(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RM4018 EMBL ABV67435.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000361 Genomic DNA. Translation: ABV67435.1.
RefSeq	YP_001490104.1. NC_009850.1.
3D structure databases
ProteinModelPortal	A8EU11.
ModBase	Search...
Protein-protein interaction databases
STRING	367737.Abu_1175.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABV67435; ABV67435; Abu_1175.
GeneID	5624766.
KEGG	abu:Abu_1175.
PATRIC	20963724. VBIArcBut20197_1163.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1160.
HOGENOM	HOG000242861.
KO	K03977.
OMA	TNVLNEV.
ProtClustDB	PRK00093.
Enzyme and pathway databases
BioCyc	ABUT367737:GHWO-1173-MONOMER.
Family and domain databases
Gene3D	3.30.300.20. 1 hit.
HAMAP	MF_00195. GTPase_Der.
InterPro	IPR016484. GTP-bd_EngA. IPR006073. GTP_binding_domain. IPR015946. KH_dom-like_a/b. IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. [Graphical view]
PANTHER	PTHR11649:SF5. PTHR11649:SF5. 1 hit.
Pfam	PF01926. MMR_HSR1. 2 hits. [Graphical view]
PIRSF	PIRSF006485. GTP-binding_EngA. 1 hit.
PRINTS	PR00326. GTP1OBG.
SUPFAM	SSF52540. SSF52540. 2 hits.
TIGRFAMs	TIGR03594. GTPase_EngA. 1 hit. TIGR00231. small_GTP. 2 hits.
ProtoNet	Search...

Entry information

Entry name

A8EU11_ARCB4

Accession

Primary (citable) accession number: A8EU11

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	May 29, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)