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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Arcobacter butzleri (strain RM4018)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotationSAAS annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotationSAAS annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotationSAAS annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. protein catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationSAAS annotation, Transferase

Enzyme and pathway databases

BioCyciABUT367737:GHWO-1093-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotationImported
Ordered Locus Names:Abu_1095Imported
OrganismiArcobacter butzleri (strain RM4018)Imported
Taxonomic identifieri367737 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeArcobacter
ProteomesiUP000001136 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi367737.Abu_1095.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiYRQGIFP.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

A8ETT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLIDKKYKI YLLDEEKFDF PTLNMMNDDL VAIGGDFHPQ RLLNAYENGI
60 70 80 90 100
FPWFIDDLGY IHWFSPQKRM VLYPENFKVS KSLRKSITNK GFVVKSNENF
110 120 130 140 150
EEVIRSCAKI KRKHEDGTWI SEEFIKAYTN LHELDIAFSI ECYLKDELVG
160 170 180 190 200
GLYGVLIGDI FCGESMFSLV PDTSKVAFYH LCQQAKQNGI KIIDCQVYND
210 220
HLASLGAFEI TRNEYFNLLK DS
Length:222
Mass (Da):25,814
Last modified:November 13, 2007 - v1
Checksum:i6DAAB9897BFA8B53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000361 Genomic DNA. Translation: ABV67355.1.
RefSeqiWP_012012798.1. NC_009850.1.
YP_001490024.1. NC_009850.1.

Genome annotation databases

EnsemblBacteriaiABV67355; ABV67355; Abu_1095.
KEGGiabu:Abu_1095.
PATRICi20963566. VBIArcBut20197_1084.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000361 Genomic DNA. Translation: ABV67355.1.
RefSeqiWP_012012798.1. NC_009850.1.
YP_001490024.1. NC_009850.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi367737.Abu_1095.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV67355; ABV67355; Abu_1095.
KEGGiabu:Abu_1095.
PATRICi20963566. VBIArcBut20197_1084.

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiYRQGIFP.
OrthoDBiEOG6WX4R3.

Enzyme and pathway databases

BioCyciABUT367737:GHWO-1093-MONOMER.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RM4018Imported.

Entry informationi

Entry nameiA8ETT1_ARCB4
AccessioniPrimary (citable) accession number: A8ETT1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: April 1, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.