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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Arcobacter butzleri (strain RM4018)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotationSAAS annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotationSAAS annotation
L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotationSAAS annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotationSAAS annotationImported, Transferase

Enzyme and pathway databases

BioCyciABUT367737:G1G6I-1098-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotationSAAS annotation (EC:2.3.2.6UniRule annotationSAAS annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotationImported
Ordered Locus Names:Abu_1095Imported
OrganismiArcobacter butzleri (strain RM4018)Imported
Taxonomic identifieri367737 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeArcobacter
Proteomesi
  • UP000001136 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi367737.Abu_1095

Structurei

3D structure databases

ProteinModelPortaliA8ETT1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

A8ETT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLIDKKYKI YLLDEEKFDF PTLNMMNDDL VAIGGDFHPQ RLLNAYENGI
60 70 80 90 100
FPWFIDDLGY IHWFSPQKRM VLYPENFKVS KSLRKSITNK GFVVKSNENF
110 120 130 140 150
EEVIRSCAKI KRKHEDGTWI SEEFIKAYTN LHELDIAFSI ECYLKDELVG
160 170 180 190 200
GLYGVLIGDI FCGESMFSLV PDTSKVAFYH LCQQAKQNGI KIIDCQVYND
210 220
HLASLGAFEI TRNEYFNLLK DS
Length:222
Mass (Da):25,814
Last modified:November 13, 2007 - v1
Checksum:i6DAAB9897BFA8B53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000361 Genomic DNA Translation: ABV67355.1
RefSeqiWP_012012798.1, NC_009850.1

Genome annotation databases

EnsemblBacteriaiABV67355; ABV67355; Abu_1095
GeneIDi24303872
KEGGiabu:Abu_1095

Similar proteinsi

Entry informationi

Entry nameiA8ETT1_ARCB4
AccessioniPrimary (citable) accession number: A8ETT1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: February 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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