A8EQZ2 (GLMM_ARCB4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Abu_0081

Organism

Arcobacter butzleri (strain RM4018) [Complete proteome] [HAMAP]

Taxonomic identifier

367737 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Arcobacter

Protein attributes

Sequence length	444 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 444	444	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000068887
Sites
	Active site	99	1	Phosphoserine intermediate By similarity
	Metal binding	99	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
Amino acid modifications
	Modified residue	99	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8EQZ2 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 7B85095EF5E4B8CB	FASTA	444	48,636
	10 20 30 40 50 60 MKLFGTDGVR GKAGDFLDAI TVLKLAKAAG IYFRKHSTTN KILVGKDTRR SGYMIENALV 70 80 90 100 110 120 SGLTAVGYDV IQIGPMPTPA IAYLTESMRC DAGIMISASH NPFEDNGIKF FDNHGNKLNT 130 140 150 160 170 180 TCEEEIENIF NDMDLMQSEQ VTGRDIGSSK RIDDVIGRYI VAIKSSFPKN LTLKGLRIIL 190 200 210 220 230 240 DCANGAAYKV GPTILEELGA DVITINNKPN GFNINENCGA MHPETVSNLV KEYRADIGLA 250 260 270 280 290 300 LDGDADRLVV IDEKGEIVDG DNLLGALSVY LKNENLLKGD ACVATVMSNK ALEDYLQKNK 310 320 330 340 350 360 ISLFRSNVGD KYVLEVMKEK GINFGGEQSG HIIFSDIAKT GDGLASALQV LALIIKSGKK 370 380 390 400 410 420 ASEILNPFSL YPQILHNMKV TEKIPLEQIT GLEEVLKPIR QKGLRDLIRY SGTENKIRLL 430 440 LEGKNKKDVE DAMQTLIAFF KKAL

References

[1]

"The complete genome sequence and analysis of the Epsilonproteobacterium Arcobacter butzleri." Miller W.G., Parker C.T., Rubenfield M., Mendz G.L., Woesten M.M.S.M., Ussery D.W., Stolz J.F., Binnewies T.T., Hallin P.F., Wang G., Malek J.A., Rogosin A., Stanker L.H., Mandrell R.E. PLoS ONE 2:E1358-E1358(2007) [PubMed: 18159241] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RM4018.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000361 Genomic DNA. Translation: ABV66366.1.
RefSeq	YP_001489035.1. NC_009850.1.
3D structure databases
ProteinModelPortal	A8EQZ2.
ModBase	Search...
Protein-protein interaction databases
STRING	A8EQZ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5624423.
GenomeReviews	Gene locus Abu_0081 in contig CP000361_GR.
KEGG	abu:Abu_0081.
PATRIC	20961520. VBIArcBut20197_0081.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	LGLDIAC.
ProtClustDB	PRK14324.
Enzyme and pathway databases
BioCyc	ABUT367737:ABU_0081-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ARCB4

Accession

Primary (citable) accession number: A8EQZ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program