Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Uncharacterized protein

Gene

abi1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_346743. Regulation of actin dynamics for phagocytic cup formation.
REACT_347216. VEGFA-VEGFR2 Pathway.
REACT_359706. RHO GTPases Activate WASPs and WAVEs.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:abi1bImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437 Componenti: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-060929-1182. abi1b.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000086077.

Family & Domainsi

Sequence similaritiesi

Contains 1 SH3 domain.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotation

Phylogenomic databases

eggNOGiNOG262939.
GeneTreeiENSGT00390000003756.
HOGENOMiHOG000293213.
HOVERGENiHBG050446.
OMAiSRVAEYC.
OrthoDBiEOG7J17ZT.
TreeFamiTF314303.

Family and domain databases

InterProiIPR028457. ABI.
IPR028456. ABI1.
IPR012849. Abl-interactor_HHR_dom.
IPR001452. SH3_domain.
IPR000727. T_SNARE_dom.
[Graphical view]
PANTHERiPTHR10460. PTHR10460. 1 hit.
PTHR10460:SF2. PTHR10460:SF2. 1 hit.
PfamiPF07815. Abi_HHR. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8E7L4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEGEKSNAE GCKMAELQML LEEEIPAGKR ALVESYQNLS RVAEYCENNY
60 70 80 90 100
VQAQDKRKAL EETKAYTTQS LASVAYQINA LANNVLQLLD IQASQLRRME
110 120 130 140 150
SSINHISQTV DIHKEKVARR EIGILTTNKN TSRTHKIIAP GNMERPVRYI
160 170 180 190 200
RKPIDYTLLD DVGHGVKQGN NQPARGGGGT LSRTNPPTQK PPSPPMAGRG
210 220 230 240 250
TLGRNTPYKT LEPVKPPVVP NDYMTSPARL GSQNSPGRTA SLNQRPRTHS
260 270 280 290 300
GSSGGSGGRE NSSNSMGIPL AVPTPSPPSM APAVPPGPGL GPIPMSQFGT
310 320 330 340 350
ISRQISRHNS STTSSSASMV SATGTYRRAP ASSSQFSVPQ PHLNGGPTFP
360 370 380 390 400
QTTMTVAPPP PPVVQLTPQI PLTGFVARVQ ENITDSPSPP PPPLPEDTPL
410 420 430 440 450
FEEAAPPPPP PPVDYDEEDA ALVHYNDPYA DGDPHWAPKS YIEKVVAIYD
460 470 480 490 500
YSKDKDDELS FMEGAIIYII KKNDDGWFEG VCNGVTGLFP GNYVESIMHY

AD
Length:502
Mass (Da):54,290
Last modified:November 13, 2007 - v1
Checksum:i42AEDB41587D5C5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX470264 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSDART00000091644; ENSDARP00000086077; ENSDARG00000062991.
ENSDART00000127940; ENSDARP00000110879; ENSDARG00000062991.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX470264 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000086077.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000091644; ENSDARP00000086077; ENSDARG00000062991.
ENSDART00000127940; ENSDARP00000110879; ENSDARG00000062991.

Organism-specific databases

ZFINiZDB-GENE-060929-1182. abi1b.

Phylogenomic databases

eggNOGiNOG262939.
GeneTreeiENSGT00390000003756.
HOGENOMiHOG000293213.
HOVERGENiHBG050446.
OMAiSRVAEYC.
OrthoDBiEOG7J17ZT.
TreeFamiTF314303.

Enzyme and pathway databases

ReactomeiREACT_346743. Regulation of actin dynamics for phagocytic cup formation.
REACT_347216. VEGFA-VEGFR2 Pathway.
REACT_359706. RHO GTPases Activate WASPs and WAVEs.

Family and domain databases

InterProiIPR028457. ABI.
IPR028456. ABI1.
IPR012849. Abl-interactor_HHR_dom.
IPR001452. SH3_domain.
IPR000727. T_SNARE_dom.
[Graphical view]
PANTHERiPTHR10460. PTHR10460. 1 hit.
PTHR10460:SF2. PTHR10460:SF2. 1 hit.
PfamiPF07815. Abi_HHR. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  3. Ensembl
    Submitted (AUG-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiA8E7L4_DANRE
AccessioniPrimary (citable) accession number: A8E7L4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: June 24, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.