A8E7H4 (A8E7H4_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Retinal homeobox protein Rx3 Ensembl ENSDARP00000069319

Submitted name:
Rx3 protein EMBL AAI63788.1

Gene names

Name:

rx3 Ensembl ENSDARP00000069319 ZFIN ZDB-GENE-990415-238

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome] Ensembl ENSDARP00000069319

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU000682.
Sequence similarities	Contains 1 homeobox DNA-binding domain. SAAS SAAS003654

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS003654 RuleBase RU000682
Domain	Homeobox SAAS SAAS003654 RuleBase RU000682
Ligand	DNA-binding SAAS SAAS003654 RuleBase RU000682
Molecular function	Developmental protein SAAS SAAS003654
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8E7H4 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 391892A526FE7A96	FASTA	292	32,758
	10 20 30 40 50 60 MRLVGSQYKD MEDRLSPSAR LVRSPGSQTR IHSIESILGF KGETLFHPAF PYGSGKTGKD 70 80 90 100 110 120 TEHLSPKKDS NKHFDGVCRS TVMVSPDLPD ADGGKLSDDE NPKKKHRRNR TTFTTFQLHE 130 140 150 160 170 180 LERAFEKSHY PDVYSREELA LKVNLPEVRV QVWFQNRRAK WRRQEKLEVS SIKLQESSML 190 200 210 220 230 240 SIPRSGPLSL GSGLPLEPWL TGPISTSSSP LQSLPSFITP QQAVPASYTP PQFLSSSTLN 250 260 270 280 290 HSLPHIGAVC PPYQCSGFMD KFSLEEADPR NTSIASLRMK AKEHIQSIGK TW

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pooled EMBL AAI63788.1.
[2]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000069319.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000069319.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248399 Genomic DNA. No translation available. BC163788 mRNA. Translation: AAI63788.1. BC163791 mRNA. Translation: AAI63791.1.
IPI	IPI00493738.
UniGene	Dr.540.
3D structure databases
SMR	A8E7H4. Positions 107-167.
ModBase	Search...
Protein-protein interaction databases
STRING	7955.ENSDARP00000069319.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000074833; ENSDARP00000069319; ENSDARG00000052893.
Organism-specific databases
ZFIN	ZDB-GENE-990415-238. rx3.
Phylogenomic databases
GeneTree	ENSGT00700000104256.
HOVERGEN	HBG021349.
OMA	KLEVSSI.
Family and domain databases
Gene3D	1.10.10.60. 1 hit.
InterPro	IPR017970. Homeobox_CS. IPR001356. Homeodomain. IPR009057. Homeodomain-like. IPR003654. OAR_dom. [Graphical view]
Pfam	PF00046. Homeobox. 1 hit. PF03826. OAR. 1 hit. [Graphical view]
SMART	SM00389. HOX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS50803. OAR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8E7H4_DANRE

Accession

Primary (citable) accession number: A8E7H4

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	April 3, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)