Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CARD11 protein

Gene

CARD11

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-BTA-1169091. Activation of NF-kappaB in B cells.
R-BTA-202424. Downstream TCR signaling.
R-BTA-2871837. FCERI mediated NF-kB activation.
R-BTA-5607764. CLEC7A (Dectin-1) signaling.

Names & Taxonomyi

Protein namesi
Submitted name:
CARD11 proteinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:CARD11Imported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 25

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000036945.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 10393CARDInterPro annotationAdd
BLAST
Domaini672 – 74776PDZ (DHR)InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili215 – 24935Sequence analysisAdd
BLAST
Coiled coili295 – 34349Sequence analysisAdd
BLAST
Coiled coili351 – 44191Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410ISRJ. Eukaryota.
ENOG41126VR. LUCA.
GeneTreeiENSGT00530000063108.
HOGENOMiHOG000111299.
HOVERGENiHBG099790.
KOiK07367.
OMAiHRMNTVM.
OrthoDBiEOG747PH5.
TreeFamiTF351139.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
2.30.42.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001315. CARD.
IPR033538. CARD11.
IPR011029. DEATH-like_dom.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
[Graphical view]
PANTHERiPTHR14559:SF4. PTHR14559:SF4. 2 hits.
PfamiPF00619. CARD. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF50156. SSF50156. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
PS50106. PDZ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8E646-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDYMETLKD EEDALWENVE CNRHMLSRYI NPAKLTPYLR QCKVIDEQDE
60 70 80 90 100
DEVLNAPMLP SKINRAGRLL DILHTKGQRG YVVFLESLEF YYPELYKLVT
110 120 130 140 150
GKEPTRRFST IVVEEGHEGL THFLMNEVIK LQQQMKAKDL QRCELLAKSR
160 170 180 190 200
QLEDEKKQLT LTRVELLTFQ ERYYKMKEER DSYNDELVKV KDDNYNLAMR
210 220 230 240 250
YAQLSEEKNM AVMRSRDLQL EIDQLKHRLN KMEEECKLER NQSLKLKNDI
260 270 280 290 300
ENRPKKEQVL ELERENEMLK TKIQELQSII QAGKRSLPDS DKAILDILEH
310 320 330 340 350
DRKEALEDRQ ELVNKIYNLQ EEVRQAEELR DKYLEEKEDL ELKCSTLGKD
360 370 380 390 400
CEMYKHRMNT VMLQLEEVER ERDQAFHSRD EAQTQYSQCL IEKDKYRKQI
410 420 430 440 450
RELEEKNDEM RIEMVRREAC IVNLESKLRR LSKDSGTLEQ SLPRNLPVTI
460 470 480 490 500
ISQNFGDTSP RTNGQEADDS STSEDSPEDN RYFLPHHPPK RRMNLKGIQL
510 520 530 540 550
QRAKSPISLK RASDFQGRGQ EEDLMDASPS SSRSLPITNS FSKMPHRSRS
560 570 580 590 600
SIMSITAEPP GNDSIVRRYK EDAPHRSTVE EDNDSGGFDA LDLDDDSHER
610 620 630 640 650
CSFGPPSIHS SSSSHQSEGL DAYDLEQVNL MFRKFSLERP FRPSVTSVGH
660 670 680 690 700
VRGPGLSVQH TTLSGDSLIS QLSLLGGNAS GSFVHSVKPG SLAEKAGLRE
710 720 730 740 750
GHQLLLLEGC IRGERQSVPL DACTKEEAHW TIQRCSGPVT LHYKVNQEGY
760 770 780 790 800
RKLLKDMEEG LITSGDSFYI RLNLNICSQL DACSMSLKCD DVVHVRDTMY
810 820 830 840 850
QDKHEWLCAR VDPFTDHDLD MGTIPSYSRA QQLLLVKLQR LMHRGSREEA
860 870 880 890 900
DTAHHTLRAL RNTLQPEEPL PTTDPRVSPR LSRASFLFGQ LLQFVSRSEN
910 920 930 940 950
KYKRMNSHER VRIVSGSPRG SLARSSLDAT KLLTEKQEEL DPESELGKNL
960 970 980 990 1000
SLIPYSLVRA FYCERRRPVL FTPTMLAKAL VQKLLNSGGA MEFTMCKPDV
1010 1020 1030 1040 1050
VTRDEFLRKQ KTETIIHSRE KNPNTFECVV PAHIEAVAAK NKHCLLEAGI
1060 1070 1080 1090 1100
SCTRDLIKSR IYPIVLFVRV SEKNIKKFRK MLPRPETEDE FLRLCRLKEK
1110 1120 1130 1140
ELEALPCLYA TVEADMWGSV EELLRVIKDK IAEEQRKTVW VDEDQL
Length:1,146
Mass (Da):132,542
Last modified:November 13, 2007 - v1
Checksum:i3149B8270C010DD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02058388 Genomic DNA. No translation available.
DAAA02058389 Genomic DNA. No translation available.
DAAA02058390 Genomic DNA. No translation available.
DAAA02058391 Genomic DNA. No translation available.
BC153839 mRNA. Translation: AAI53840.1.
RefSeqiNP_001103266.1. NM_001109796.2.
UniGeneiBt.43438.

Genome annotation databases

EnsembliENSBTAT00000037106; ENSBTAP00000036945; ENSBTAG00000014698.
GeneIDi515377.
KEGGibta:515377.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02058388 Genomic DNA. No translation available.
DAAA02058389 Genomic DNA. No translation available.
DAAA02058390 Genomic DNA. No translation available.
DAAA02058391 Genomic DNA. No translation available.
BC153839 mRNA. Translation: AAI53840.1.
RefSeqiNP_001103266.1. NM_001109796.2.
UniGeneiBt.43438.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000036945.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000037106; ENSBTAP00000036945; ENSBTAG00000014698.
GeneIDi515377.
KEGGibta:515377.

Organism-specific databases

CTDi84433.

Phylogenomic databases

eggNOGiENOG410ISRJ. Eukaryota.
ENOG41126VR. LUCA.
GeneTreeiENSGT00530000063108.
HOGENOMiHOG000111299.
HOVERGENiHBG099790.
KOiK07367.
OMAiHRMNTVM.
OrthoDBiEOG747PH5.
TreeFamiTF351139.

Enzyme and pathway databases

ReactomeiR-BTA-1169091. Activation of NF-kappaB in B cells.
R-BTA-202424. Downstream TCR signaling.
R-BTA-2871837. FCERI mediated NF-kB activation.
R-BTA-5607764. CLEC7A (Dectin-1) signaling.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
2.30.42.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001315. CARD.
IPR033538. CARD11.
IPR011029. DEATH-like_dom.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
[Graphical view]
PANTHERiPTHR14559:SF4. PTHR14559:SF4. 2 hits.
PfamiPF00619. CARD. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF50156. SSF50156. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
PS50106. PDZ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HerefordImported.
    Tissue: ThymusImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  3. Ensembl
    Submitted (MAR-2016) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiA8E646_BOVIN
AccessioniPrimary (citable) accession number: A8E646
Secondary accession number(s): F1MQU2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: July 6, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.