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Protein
Submitted name:

CARD11 protein

Gene

CARD11

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-BTA-1169091 Activation of NF-kappaB in B cells
R-BTA-202424 Downstream TCR signaling
R-BTA-2871837 FCERI mediated NF-kB activation

Names & Taxonomyi

Protein namesi
Submitted name:
CARD11 proteinImported
Submitted name:
Caspase recruitment domain family member 11Imported
Gene namesi
Name:CARD11Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 25

Organism-specific databases

VGNCiVGNC:26761 CARD11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSBTAG00000014698

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000036945

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 103CARDInterPro annotationAdd BLAST93
Domaini672 – 747PDZInterPro annotationAdd BLAST76

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili215 – 249Sequence analysisAdd BLAST35
Coiled coili259 – 279Sequence analysisAdd BLAST21
Coiled coili295 – 343Sequence analysisAdd BLAST49
Coiled coili351 – 441Sequence analysisAdd BLAST91

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410ISRJ Eukaryota
ENOG41126VR LUCA
GeneTreeiENSGT00530000063108
HOGENOMiHOG000111299
HOVERGENiHBG099790
KOiK07367
OMAiEACIVNL
OrthoDBiEOG091G0T58
TreeFamiTF351139

Family and domain databases

InterProiView protein in InterPro
IPR001315 CARD
IPR033538 CARD11
IPR011029 DEATH-like_dom_sf
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR036034 PDZ_sf
PANTHERiPTHR14559:SF4 PTHR14559:SF4, 1 hit
PfamiView protein in Pfam
PF00619 CARD, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF50156 SSF50156, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit
PS50106 PDZ, 1 hit

Sequencei

Sequence statusi: Complete.

A8E646-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDYMETLKD EEDALWENVE CNRHMLSRYI NPAKLTPYLR QCKVIDEQDE
60 70 80 90 100
DEVLNAPMLP SKINRAGRLL DILHTKGQRG YVVFLESLEF YYPELYKLVT
110 120 130 140 150
GKEPTRRFST IVVEEGHEGL THFLMNEVIK LQQQMKAKDL QRCELLAKSR
160 170 180 190 200
QLEDEKKQLT LTRVELLTFQ ERYYKMKEER DSYNDELVKV KDDNYNLAMR
210 220 230 240 250
YAQLSEEKNM AVMRSRDLQL EIDQLKHRLN KMEEECKLER NQSLKLKNDI
260 270 280 290 300
ENRPKKEQVL ELERENEMLK TKIQELQSII QAGKRSLPDS DKAILDILEH
310 320 330 340 350
DRKEALEDRQ ELVNKIYNLQ EEVRQAEELR DKYLEEKEDL ELKCSTLGKD
360 370 380 390 400
CEMYKHRMNT VMLQLEEVER ERDQAFHSRD EAQTQYSQCL IEKDKYRKQI
410 420 430 440 450
RELEEKNDEM RIEMVRREAC IVNLESKLRR LSKDSGTLEQ SLPRNLPVTI
460 470 480 490 500
ISQNFGDTSP RTNGQEADDS STSEDSPEDN RYFLPHHPPK RRMNLKGIQL
510 520 530 540 550
QRAKSPISLK RASDFQGRGQ EEDLMDASPS SSRSLPITNS FSKMPHRSRS
560 570 580 590 600
SIMSITAEPP GNDSIVRRYK EDAPHRSTVE EDNDSGGFDA LDLDDDSHER
610 620 630 640 650
CSFGPPSIHS SSSSHQSEGL DAYDLEQVNL MFRKFSLERP FRPSVTSVGH
660 670 680 690 700
VRGPGLSVQH TTLSGDSLIS QLSLLGGNAS GSFVHSVKPG SLAEKAGLRE
710 720 730 740 750
GHQLLLLEGC IRGERQSVPL DACTKEEAHW TIQRCSGPVT LHYKVNQEGY
760 770 780 790 800
RKLLKDMEEG LITSGDSFYI RLNLNICSQL DACSMSLKCD DVVHVRDTMY
810 820 830 840 850
QDKHEWLCAR VDPFTDHDLD MGTIPSYSRA QQLLLVKLQR LMHRGSREEA
860 870 880 890 900
DTAHHTLRAL RNTLQPEEPL PTTDPRVSPR LSRASFLFGQ LLQFVSRSEN
910 920 930 940 950
KYKRMNSHER VRIVSGSPRG SLARSSLDAT KLLTEKQEEL DPESELGKNL
960 970 980 990 1000
SLIPYSLVRA FYCERRRPVL FTPTMLAKAL VQKLLNSGGA MEFTMCKPDV
1010 1020 1030 1040 1050
VTRDEFLRKQ KTETIIHSRE KNPNTFECVV PAHIEAVAAK NKHCLLEAGI
1060 1070 1080 1090 1100
SCTRDLIKSR IYPIVLFVRV SEKNIKKFRK MLPRPETEDE FLRLCRLKEK
1110 1120 1130 1140
ELEALPCLYA TVEADMWGSV EELLRVIKDK IAEEQRKTVW VDEDQL
Length:1,146
Mass (Da):132,542
Last modified:November 13, 2007 - v1
Checksum:i3149B8270C010DD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02058388 Genomic DNA No translation available.
DAAA02058389 Genomic DNA No translation available.
DAAA02058390 Genomic DNA No translation available.
DAAA02058391 Genomic DNA No translation available.
BC153839 mRNA Translation: AAI53840.1
RefSeqiNP_001103266.1, NM_001109796.2
UniGeneiBt.43438

Genome annotation databases

EnsembliENSBTAT00000037106; ENSBTAP00000036945; ENSBTAG00000014698
GeneIDi515377
KEGGibta:515377

Similar proteinsi

Entry informationi

Entry nameiA8E646_BOVIN
AccessioniPrimary (citable) accession number: A8E646
Secondary accession number(s): F1MQU2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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