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Protein
Submitted name:

Gamt protein

Gene

gamt

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei18 – 181S-adenosyl-L-methionineUniRule annotation
Binding sitei40 – 401SubstrateUniRule annotation
Binding sitei44 – 441SubstrateUniRule annotation
Binding sitei48 – 481S-adenosyl-L-methionineUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Gamt proteinImported
Submitted name:
Guanidinoacetate N-methyltransferaseImported
Gene namesi
Name:gamtImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 11

Organism-specific databases

ZFINiZDB-GENE-051030-97. gamt.

Expressioni

Gene expression databases

BgeeiA8E5I0.
ExpressionAtlasiA8E5I0. differential.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000095135.

Structurei

3D structure databases

SMRiA8E5I0. Positions 6-233.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 234234RMT2 (arginine N-methyltransferase 2-like)InterPro annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni67 – 726S-adenosyl-L-methionine bindingUniRule annotation
Regioni88 – 903S-adenosyl-L-methionine bindingUniRule annotation
Regioni115 – 1162S-adenosyl-L-methionine bindingUniRule annotation
Regioni169 – 1702Substrate bindingUniRule annotation

Phylogenomic databases

eggNOGiENOG410ISNM. Eukaryota.
ENOG410XPX4. LUCA.
HOVERGENiHBG005801.
KOiK00542.
OMAiRYYAFPQ.
PhylomeDBiA8E5I0.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR016550. GuanidinoAc_N-MeTrfase.
IPR026480. RMT2_dom.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PIRSFiPIRSF009285. GAMT. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51559. SAM_RMT2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8E5I0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAAQPIFSK GENCKQVWHD ANADYNAADT HLEIMGKPVM ERWETPYMHS
60 70 80 90 100
LATVAASKGG RVLEIGFGMA IAATKVESFP IEEHWIIECN DGVFQRLQEW
110 120 130 140 150
AKSQPHKVVP LKGLWEEVAP TLPDNHFDGI LYDTYPLSEE TWHTHQFNFI
160 170 180 190 200
KAHAHRMLKP GGVLTYCNLT SWGELLKNKY DNIDKMFQET QVPHLLEAGF
210 220 230
KKEKISTTLM DISPPSECKY YSFNKMITPT IIKE
Length:234
Mass (Da):26,743
Last modified:November 13, 2007 - v1
Checksum:iC998B222A2FA1E1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323045 Genomic DNA. No translation available.
BC153601 mRNA. Translation: AAI53602.1.
RefSeqiNP_001099065.1. NM_001105595.1.
UniGeneiDr.28451.

Genome annotation databases

EnsembliENSDART00000104360; ENSDARP00000095135; ENSDARG00000070844.
GeneIDi796865.
KEGGidre:796865.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323045 Genomic DNA. No translation available.
BC153601 mRNA. Translation: AAI53602.1.
RefSeqiNP_001099065.1. NM_001105595.1.
UniGeneiDr.28451.

3D structure databases

SMRiA8E5I0. Positions 6-233.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000095135.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000104360; ENSDARP00000095135; ENSDARG00000070844.
GeneIDi796865.
KEGGidre:796865.

Organism-specific databases

CTDi2593.
ZFINiZDB-GENE-051030-97. gamt.

Phylogenomic databases

eggNOGiENOG410ISNM. Eukaryota.
ENOG410XPX4. LUCA.
HOVERGENiHBG005801.
KOiK00542.
OMAiRYYAFPQ.
PhylomeDBiA8E5I0.

Gene expression databases

BgeeiA8E5I0.
ExpressionAtlasiA8E5I0. differential.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR016550. GuanidinoAc_N-MeTrfase.
IPR026480. RMT2_dom.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PIRSFiPIRSF009285. GAMT. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51559. SAM_RMT2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Whole bodyImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  3. Ensembl
    Submitted (AUG-2015) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiA8E5I0_DANRE
AccessioniPrimary (citable) accession number: A8E5I0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: June 8, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.