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Protein
Submitted name:

Intersectin 1 short form variant 13

Gene

ITSN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Intersectin 1 short form variant 13Imported
Submitted name:
Intersectin-1Imported
Gene namesi
Name:ITSN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 21

Organism-specific databases

HGNCiHGNC:6183. ITSN1.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118985.
HOVERGENiHBG052159.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF14604. SH3_9. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8CTZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ
60 70 80 90 100
SGLPQPVLAQ IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP
110 120 130 140 150
VMKQQPVAIS SAPAFAAVPP LANGAPPVIQ PLPAFAHPAA TLPKSSSFSR
160 170 180 190 200
SGPGSQLNTK LQKAQSFDVA SVPPVAEWAV PQSSRLKYRQ LFNSHDKTMS
210 220 230 240 250
GHLTGPQART ILMQSSLPQA QLASIWNLSD IDQDGKLTAE EFILAMHLID
260 270 280 290 300
VAMSGQPLPP VLPPEYIPPS FRRVRSGSGI SVISSTSVDQ RLPEEPVLED
310 320 330 340 350
EQQQLEKKLP VTFEDKKREN FERGNLELEK RRQALLEQQR KEQERLAQLE
360 370 380 390 400
RAEQERKERE RQEQERKRQL ELEKQLEKQR ELERQREEER RKEIERREAA
410 420 430 440 450
KRELERQRQL EWERNRRQEL LNQRNKEQED IVVLKAKKKT LEFELEALND
460 470 480 490 500
KKHQLEGKLQ DIRCRLTTQR QEIESTNKSR ELRIAEITHL QQQLQESQQM
510 520 530 540 550
LGRLIPEKQI LNDQLKQVQQ NSLHRDSLVT LKRALEAKEL ARQHLRDQLD
560 570 580 590 600
EVEKETRSKL QEIDIFNNQL KELREIHNKQ QLQKQKSMEA ERLKQKEQER
610 620 630 640 650
KIIELEKQKE EAQRRAQERD KQWLEHVQQE DEHQRPRKLH EEEKLKREES
660 670 680 690 700
VKKKDGEEKG KQEAQDKLGR LFHQHQEPAK PAVQAPWSTA EKGPLTISAQ
710 720 730 740 750
ENVKVVYYRA LYPFESRSHD EITIQPGDIV MVDESQTGEP GWLGGELKGK
760 770 780 790 800
TGWFPANYAE KIPENEVPAP VKPVTDSTSA PAPKLALRET PAPLAVTSSE
810 820 830 840 850
PSTTPNNWAD FSSTWPTSTN EKPETDNWDA WAAQPSLTVP SAGQLRQRSA
860 870
FTPATATGSS PSPVLGQHGF WFFRESC
Length:877
Mass (Da):100,705
Last modified:November 13, 2007 - v1
Checksum:i763906D35F88716D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000308 Genomic DNA. No translation available.
AP000309 Genomic DNA. No translation available.
AP000310 Genomic DNA. No translation available.
AP000311 Genomic DNA. No translation available.
AP000312 Genomic DNA. No translation available.
AP000313 Genomic DNA. No translation available.
KF457227 Genomic DNA. No translation available.
KF511399 Genomic DNA. No translation available.
KF511404 Genomic DNA. No translation available.
EU120736 mRNA. Translation: ABV24869.1.
UniGeneiHs.160324.

Genome annotation databases

EnsembliENST00000381285; ENSP00000370685; ENSG00000205726.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000308 Genomic DNA. No translation available.
AP000309 Genomic DNA. No translation available.
AP000310 Genomic DNA. No translation available.
AP000311 Genomic DNA. No translation available.
AP000312 Genomic DNA. No translation available.
AP000313 Genomic DNA. No translation available.
KF457227 Genomic DNA. No translation available.
KF511399 Genomic DNA. No translation available.
KF511404 Genomic DNA. No translation available.
EU120736 mRNA. Translation: ABV24869.1.
UniGeneiHs.160324.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000381285; ENSP00000370685; ENSG00000205726.

Organism-specific databases

HGNCiHGNC:6183. ITSN1.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118985.
HOVERGENiHBG052159.

Miscellaneous databases

NextBioi35463619.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF14604. SH3_9. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 21."
    Chromosome 21 mapping and sequencing consortium
    Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A.
    , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.
    Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Structural diversity and differential expression of novel human intersectin 1 isoforms."
    Kropyvko S., Gerasymchuk D., Skrypkina I., Dergai M., Dergai O., Nikolaienko O., Rynditch A., Tsyba L.
    Mol. Biol. Rep. 37:2789-2796(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA8CTZ0_HUMAN
AccessioniPrimary (citable) accession number: A8CTZ0
Secondary accession number(s): E9PD98
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: March 4, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationMaxQB annotation, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.