Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Beta-amyrin synthase

Gene

BAS

Organism
Bruguiera gymnorhiza (Burma mangrove) (Rhizophora gymnorhiza)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Oxidosqualene cyclase involved in the biosynthesis of beta-amyrin.1 Publication

Catalytic activityi

(3S)-2,3-epoxy-2,3-dihydrosqualene = beta-amyrin.1 Publication

GO - Molecular functioni

  • beta-amyrin synthase activity Source: UniProtKB

GO - Biological processi

  • triterpenoid biosynthetic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14451.
BRENDAi5.4.99.39. 1002.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-amyrin synthase (EC:5.4.99.39)
Short name:
BgbAS
Gene namesi
Name:BAS
OrganismiBruguiera gymnorhiza (Burma mangrove) (Rhizophora gymnorhiza)
Taxonomic identifieri39984 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesRhizophoraceaeBruguiera

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 759759Beta-amyrin synthasePRO_0000412989Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA8CDT2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati148 – 18942PFTB 1Add
BLAST
Repeati514 – 55946PFTB 2Add
BLAST
Repeati591 – 63141PFTB 3Add
BLAST
Repeati640 – 68142PFTB 4Add
BLAST

Sequence similaritiesi

Belongs to the terpene cyclase/mutase family.Curated
Contains 4 PFTB repeats.Curated

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di1.50.10.20. 2 hits.
InterProiIPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view]
PfamiPF00432. Prenyltrans. 1 hit.
[Graphical view]
SUPFAMiSSF48239. SSF48239. 2 hits.
TIGRFAMsiTIGR01787. squalene_cyclas. 1 hit.

Sequencei

Sequence statusi: Complete.

A8CDT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRIKIAEGG KDPYLYSTNN YVGRQTWEFD PDAGTPEERA EVEEARQNFY
60 70 80 90 100
KNRYQVKPCG DLLWRLQFLG EKNFEQTIPQ VRIEEGEGIT YEKATRALRR
110 120 130 140 150
TVQFFSALQA SDGHWPAEIA GPLFFLPPLV MCVYITGHLD AVFPAEHRKE
160 170 180 190 200
ILRYIYYHQN EDGGWGLHIE GHSTMFCTAL NYICMRIIGE GPNGGQDDAC
210 220 230 240 250
ARARKWIHDH GSVTNIPSWG KTWLSILGVY DWSGSNPMPP EFWMLPSFLP
260 270 280 290 300
MHPAKMWCYC RMVYMPMSYL YGKRFVGPIT PLIQQLREEL FTQPYDQINW
310 320 330 340 350
KKTRHQCAPE DLYYPHPFVQ DLIWDCLYIF TEPLLTRWPL NEIIRKKALE
360 370 380 390 400
VTMKHIHYED ESSRYITIGC VEKVLCMLAC WVEDPNGDYF KKHLARIPDY
410 420 430 440 450
IWVAEDGMKM QSFGSQEWDT GFAIQALLAT NLTDEIGDVL RRGHDFIKKS
460 470 480 490 500
QVRDNPSGDF KSMYRHISKG SWTFSDQDHG WQVSDCTAEG LKCCLLFSMM
510 520 530 540 550
PPEIVGEHMV PERLYDSVNV LLSLQSKNGG LSAWEPAGAQ EWLELLNPTE
560 570 580 590 600
FFADIVIEHE YVECTSSAIH ALVLFKKLYP GHRKKEIDNF IVNAVRYLES
610 620 630 640 650
IQTSDGGWYG NWGVCFTYGT WFALGGLAAA GKTYNNCLAM RKAVDFLLRI
660 670 680 690 700
QRDNGGWGES YLSCPEKRYV PLEGNRSNLV HTAWALMALI HAGQMDRDPT
710 720 730 740 750
PLHRAARLMI NSQLEDGDFP QQEITGVFMK NCMLHYAAYR NIYPLWALAE

YRRRVPLPS
Length:759
Mass (Da):87,665
Last modified:November 13, 2007 - v1
Checksum:i9335B3C84943318B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB289585 mRNA. Translation: BAF80443.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB289585 mRNA. Translation: BAF80443.1.

3D structure databases

ProteinModelPortaliA8CDT2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14451.
BRENDAi5.4.99.39. 1002.

Family and domain databases

Gene3Di1.50.10.20. 2 hits.
InterProiIPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view]
PfamiPF00432. Prenyltrans. 1 hit.
[Graphical view]
SUPFAMiSSF48239. SSF48239. 2 hits.
TIGRFAMsiTIGR01787. squalene_cyclas. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae."
    Basyuni M., Oku H., Tsujimoto E., Kinjo K., Baba S., Takara K.
    FEBS J. 274:5028-5042(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, CATALYTIC ACTIVITY.
    Tissue: Leaf.

Entry informationi

Entry nameiBAS_BRUGY
AccessioniPrimary (citable) accession number: A8CDT2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: November 13, 2007
Last modified: May 27, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.