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A8CDT2 (BAS_BRUGY) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-amyrin synthase

Short name=BgbAS
EC=5.4.99.39
Gene names
Name:BAS
OrganismBruguiera gymnorhiza (Burma mangrove) (Rhizophora gymnorhiza)
Taxonomic identifier39984 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesRhizophoraceaeBruguiera

Protein attributes

Sequence length759 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Oxidosqualene cyclase involved in the biosynthesis of beta-amyrin. Ref.1

Catalytic activity

(3S)-2,3-epoxy-2,3-dihydrosqualene = beta-amyrin. Ref.1

Sequence similarities

Belongs to the terpene cyclase/mutase family.

Contains 4 PFTB repeats.

Ontologies

Keywords
   DomainRepeat
   Molecular functionIsomerase
Gene Ontology (GO)
   Biological_processtriterpenoid biosynthetic process

Inferred from direct assay Ref.1. Source: UniProtKB

   Molecular_functionbeta-amyrin synthase activity

Inferred from direct assay Ref.1. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 759759Beta-amyrin synthase
PRO_0000412989

Regions

Repeat148 – 18942PFTB 1
Repeat514 – 55946PFTB 2
Repeat591 – 63141PFTB 3
Repeat640 – 68142PFTB 4

Sequences

Sequence LengthMass (Da)Tools
A8CDT2 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 9335B3C84943318B

FASTA75987,665
        10         20         30         40         50         60 
MWRIKIAEGG KDPYLYSTNN YVGRQTWEFD PDAGTPEERA EVEEARQNFY KNRYQVKPCG 

        70         80         90        100        110        120 
DLLWRLQFLG EKNFEQTIPQ VRIEEGEGIT YEKATRALRR TVQFFSALQA SDGHWPAEIA 

       130        140        150        160        170        180 
GPLFFLPPLV MCVYITGHLD AVFPAEHRKE ILRYIYYHQN EDGGWGLHIE GHSTMFCTAL 

       190        200        210        220        230        240 
NYICMRIIGE GPNGGQDDAC ARARKWIHDH GSVTNIPSWG KTWLSILGVY DWSGSNPMPP 

       250        260        270        280        290        300 
EFWMLPSFLP MHPAKMWCYC RMVYMPMSYL YGKRFVGPIT PLIQQLREEL FTQPYDQINW 

       310        320        330        340        350        360 
KKTRHQCAPE DLYYPHPFVQ DLIWDCLYIF TEPLLTRWPL NEIIRKKALE VTMKHIHYED 

       370        380        390        400        410        420 
ESSRYITIGC VEKVLCMLAC WVEDPNGDYF KKHLARIPDY IWVAEDGMKM QSFGSQEWDT 

       430        440        450        460        470        480 
GFAIQALLAT NLTDEIGDVL RRGHDFIKKS QVRDNPSGDF KSMYRHISKG SWTFSDQDHG 

       490        500        510        520        530        540 
WQVSDCTAEG LKCCLLFSMM PPEIVGEHMV PERLYDSVNV LLSLQSKNGG LSAWEPAGAQ 

       550        560        570        580        590        600 
EWLELLNPTE FFADIVIEHE YVECTSSAIH ALVLFKKLYP GHRKKEIDNF IVNAVRYLES 

       610        620        630        640        650        660 
IQTSDGGWYG NWGVCFTYGT WFALGGLAAA GKTYNNCLAM RKAVDFLLRI QRDNGGWGES 

       670        680        690        700        710        720 
YLSCPEKRYV PLEGNRSNLV HTAWALMALI HAGQMDRDPT PLHRAARLMI NSQLEDGDFP 

       730        740        750 
QQEITGVFMK NCMLHYAAYR NIYPLWALAE YRRRVPLPS 

« Hide

References

[1]"Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae."
Basyuni M., Oku H., Tsujimoto E., Kinjo K., Baba S., Takara K.
FEBS J. 274:5028-5042(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, CATALYTIC ACTIVITY.
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB289585 mRNA. Translation: BAF80443.1.

3D structure databases

ProteinModelPortalA8CDT2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-14451.

Family and domain databases

Gene3D1.50.10.20. 2 hits.
InterProIPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view]
PfamPF00432. Prenyltrans. 1 hit.
[Graphical view]
SUPFAMSSF48239. SSF48239. 2 hits.
TIGRFAMsTIGR01787. squalene_cyclas. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBAS_BRUGY
AccessionPrimary (citable) accession number: A8CDT2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: November 13, 2007
Last modified: April 16, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families