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A8C981

- TARS_RHISY

UniProt

A8C981 - TARS_RHISY

Protein

Taraxerol synthase

Gene

M2

Organism
Rhizophora stylosa (Bakau) (Red mangrove)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (13 Nov 2007)
      Previous versions | rss
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    Functioni

    Multifunctional triterpene synthase producing taraxerol, beta-amyrin and lupeol in the ratio 70:17:13.

    Catalytic activityi

    (3S)-2,3-epoxy-2,3-dihydrosqualene = taraxerol.

    GO - Molecular functioni

    1. intramolecular transferase activity Source: InterPro

    Keywords - Molecular functioni

    Isomerase

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-14454.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Taraxerol synthase (EC:5.4.99.35)
    Short name:
    RsM2
    Gene namesi
    Name:M2
    OrganismiRhizophora stylosa (Bakau) (Red mangrove)
    Taxonomic identifieri98588 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesRhizophoraceaeRhizophora

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 771771Taraxerol synthasePRO_0000412988Add
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati150 – 19142PFTB 1Add
    BLAST
    Repeati516 – 56146PFTB 2Add
    BLAST
    Repeati642 – 68342PFTB 3Add
    BLAST

    Sequence similaritiesi

    Belongs to the terpene cyclase/mutase family.Curated
    Contains 3 PFTB repeats.Curated

    Keywords - Domaini

    Repeat

    Family and domain databases

    Gene3Di1.50.10.20. 2 hits.
    InterProiIPR001330. Prenyltrans.
    IPR018333. Squalene_cyclase.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    [Graphical view]
    PfamiPF00432. Prenyltrans. 1 hit.
    [Graphical view]
    SUPFAMiSSF48239. SSF48239. 2 hits.
    TIGRFAMsiTIGR01787. squalene_cyclas. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A8C981-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGVWRLKIGE GANNPYLTST NNFVGRQTWV FEPDGGTPEE RDQVEEARQN    50
    YFKNRFRVRP CSDLLWQMQF LREKNFRQKI PQVKVRDGEE INYETVTNAI 100
    RRSAHYLSAT QSSDGFWPAD ASAPVFYLAP WVIGLYVIGH LNTVFPAEHQ 150
    KEILRYIYCH QNEDGGWGLH YEDGGTMFGT AFNYVCMRIL GEGPGGGRDN 200
    ACERARKGIL DHGGVTYIPS GGKTWLAMLG VFDWSGCNPM PPEFWMLPPF 250
    FPMHPAQMWC YCRIVYMPMS YLYGRRFVGP ITPLVQQLRE ELHTQPFHEI 300
    EWSKARHLCA KEDLFHRRPW IQELFWDCLH TFAEPLLTRW PLNNFIREKA 350
    LKITMEHVHY DDKASHYINP GSVEKVICMV ACWVEDPSGE PFQRHLARIS 400
    DYVWIAEDGM RITGIGSQTW DAALSIQALI ACNLIEEMGP TLKKGYDFLK 450
    NSQAKDNPPG DFKRMYRHFG KGAWAFSSQD YGVIALDCTA ESLMCCLHFS 500
    MMPPEIVGEK LEPEKLYLAV DFILSLQSKN GGLTCWEPAR GGKWLEVLNP 550
    LEFFENIVVE HEYVEVTASA INALVMFKKR YPGYREKEIE HFISKAVHYL 600
    IQTQFPNGPW YGVWGICFMY GTYFALKGLA AAGNTYANCP AIPKAVDFLL 650
    KTQCQDGGWG ESYLSGTTKV YTPLEGNRSN LVQTAWALMG LIHSGQAERD 700
    PTPLHRSAKL LINSQTSDGD FPQQDSTGLL KGSCAMHYAA YRNIFPLWAL 750
    AAYRTHVLGL TSKAHSSAVM E 771
    Length:771
    Mass (Da):87,831
    Last modified:November 13, 2007 - v1
    Checksum:i8515AFA482981022
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB263204 mRNA. Translation: BAF80442.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB263204 mRNA. Translation: BAF80442.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-14454.

    Family and domain databases

    Gene3Di 1.50.10.20. 2 hits.
    InterProi IPR001330. Prenyltrans.
    IPR018333. Squalene_cyclase.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    [Graphical view ]
    Pfami PF00432. Prenyltrans. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48239. SSF48239. 2 hits.
    TIGRFAMsi TIGR01787. squalene_cyclas. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae."
      Basyuni M., Oku H., Tsujimoto E., Kinjo K., Baba S., Takara K.
      FEBS J. 274:5028-5042(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Leaf.

    Entry informationi

    Entry nameiTARS_RHISY
    AccessioniPrimary (citable) accession number: A8C981
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 19, 2011
    Last sequence update: November 13, 2007
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3