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A8C981

- TARS_RHISY

UniProt

A8C981 - TARS_RHISY

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Protein

Taraxerol synthase

Gene
M2
Organism
Rhizophora stylosa (Bakau) (Red mangrove)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Multifunctional triterpene synthase producing taraxerol, beta-amyrin and lupeol in the ratio 70:17:13.

Catalytic activityi

(3S)-2,3-epoxy-2,3-dihydrosqualene = taraxerol.

GO - Molecular functioni

  1. intramolecular transferase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14454.

Names & Taxonomyi

Protein namesi
Recommended name:
Taraxerol synthase (EC:5.4.99.35)
Short name:
RsM2
Gene namesi
Name:M2
OrganismiRhizophora stylosa (Bakau) (Red mangrove)
Taxonomic identifieri98588 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesRhizophoraceaeRhizophora

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 771771Taraxerol synthasePRO_0000412988Add
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati150 – 19142PFTB 1Add
BLAST
Repeati516 – 56146PFTB 2Add
BLAST
Repeati642 – 68342PFTB 3Add
BLAST

Sequence similaritiesi

Contains 3 PFTB repeats.

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di1.50.10.20. 2 hits.
InterProiIPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view]
PfamiPF00432. Prenyltrans. 1 hit.
[Graphical view]
SUPFAMiSSF48239. SSF48239. 2 hits.
TIGRFAMsiTIGR01787. squalene_cyclas. 1 hit.

Sequencei

Sequence statusi: Complete.

A8C981-1 [UniParc]FASTAAdd to Basket

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MGVWRLKIGE GANNPYLTST NNFVGRQTWV FEPDGGTPEE RDQVEEARQN    50
YFKNRFRVRP CSDLLWQMQF LREKNFRQKI PQVKVRDGEE INYETVTNAI 100
RRSAHYLSAT QSSDGFWPAD ASAPVFYLAP WVIGLYVIGH LNTVFPAEHQ 150
KEILRYIYCH QNEDGGWGLH YEDGGTMFGT AFNYVCMRIL GEGPGGGRDN 200
ACERARKGIL DHGGVTYIPS GGKTWLAMLG VFDWSGCNPM PPEFWMLPPF 250
FPMHPAQMWC YCRIVYMPMS YLYGRRFVGP ITPLVQQLRE ELHTQPFHEI 300
EWSKARHLCA KEDLFHRRPW IQELFWDCLH TFAEPLLTRW PLNNFIREKA 350
LKITMEHVHY DDKASHYINP GSVEKVICMV ACWVEDPSGE PFQRHLARIS 400
DYVWIAEDGM RITGIGSQTW DAALSIQALI ACNLIEEMGP TLKKGYDFLK 450
NSQAKDNPPG DFKRMYRHFG KGAWAFSSQD YGVIALDCTA ESLMCCLHFS 500
MMPPEIVGEK LEPEKLYLAV DFILSLQSKN GGLTCWEPAR GGKWLEVLNP 550
LEFFENIVVE HEYVEVTASA INALVMFKKR YPGYREKEIE HFISKAVHYL 600
IQTQFPNGPW YGVWGICFMY GTYFALKGLA AAGNTYANCP AIPKAVDFLL 650
KTQCQDGGWG ESYLSGTTKV YTPLEGNRSN LVQTAWALMG LIHSGQAERD 700
PTPLHRSAKL LINSQTSDGD FPQQDSTGLL KGSCAMHYAA YRNIFPLWAL 750
AAYRTHVLGL TSKAHSSAVM E 771
Length:771
Mass (Da):87,831
Last modified:November 13, 2007 - v1
Checksum:i8515AFA482981022
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB263204 mRNA. Translation: BAF80442.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB263204 mRNA. Translation: BAF80442.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-14454.

Family and domain databases

Gene3Di 1.50.10.20. 2 hits.
InterProi IPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view ]
Pfami PF00432. Prenyltrans. 1 hit.
[Graphical view ]
SUPFAMi SSF48239. SSF48239. 2 hits.
TIGRFAMsi TIGR01787. squalene_cyclas. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae."
    Basyuni M., Oku H., Tsujimoto E., Kinjo K., Baba S., Takara K.
    FEBS J. 274:5028-5042(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Leaf.

Entry informationi

Entry nameiTARS_RHISY
AccessioniPrimary (citable) accession number: A8C981
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: November 13, 2007
Last modified: April 16, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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