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A8C980

- GERS_RHISY

UniProt

A8C980 - GERS_RHISY

Protein

Germanicol synthase

Gene

M1

Organism
Rhizophora stylosa (Bakau) (Red mangrove)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (13 Nov 2007)
      Previous versions | rss
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    Functioni

    Multifunctional triterpene synthase producing germanicol, beta-amyrin and lupeol in the ratio 63:33:4.1 Publication

    Catalytic activityi

    (3S)-2,3-epoxy-2,3-dihydrosqualene = germanicol.1 Publication

    GO - Molecular functioni

    1. intramolecular transferase activity Source: InterPro

    Keywords - Molecular functioni

    Isomerase

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-14453.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Germanicol synthase (EC:5.4.99.34)
    Short name:
    RsM1
    Gene namesi
    Name:M1
    OrganismiRhizophora stylosa (Bakau) (Red mangrove)
    Taxonomic identifieri98588 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesRhizophoraceaeRhizophora

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 759759Germanicol synthasePRO_0000412987Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliA8C980.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the terpene cyclase/mutase family.Curated

    Keywords - Domaini

    Repeat

    Family and domain databases

    Gene3Di1.50.10.20. 2 hits.
    InterProiIPR001330. Prenyltrans.
    IPR018333. Squalene_cyclase.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    [Graphical view]
    PfamiPF00432. Prenyltrans. 1 hit.
    [Graphical view]
    SUPFAMiSSF48239. SSF48239. 2 hits.
    TIGRFAMsiTIGR01787. squalene_cyclas. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A8C980-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWRLKIAEGG NDPYLYSTNN YVGRQIWEFD PDAGTPEERA KAEEARQNFY    50
    KNRYQVKPSG DLLWRLQFLR EKNFKQTIPQ VRIEEGEEIT REKATTALRR 100
    AVQFFSALQA SDGHWPAENA GPLFFLPPLV MCMCITGHLD TVFPAEHRKE 150
    ILRYIYYHQN EDGGWGLHIE GHSTMFCTAL NYICMRILGE GPNGGQDDAC 200
    TRARKWIHDH GSVTNIPSWG KTWLSILGVY DWSGCNPMPP EFWMLPSFLP 250
    MHPAKMWCYC RMVYMPMSYL YGKRFVGLIT PLIQQLREEL FTQPYDQINW 300
    KKNCHQCAPE DLYYPHPFIQ DLIWDCLYIS MEPLLTRWPL NMIIRKKALE 350
    LTMKHIHYED GSSRYITIGC VEKVLCMLAC WVEDPNGDYF KKHLARIPDY 400
    IWVAEDGMKM QSFGSQQWDT GFAIQALLAT NLTDEIGGVL RRGHDFIKKS 450
    QVQDNPSGDF KSMYRHISKG SWTFSDQDHG WQVSDCTAEG LKCCLLFSMM 500
    PPEIVGEHME PERLYDSVNV LLSLQSKNGG LSAWEPAGAQ DWLELLNPTE 550
    FFADIVIEHE YVERTSSAIH ALVLFKKLYP GHRKKEIEDF IAKSVRFLES 600
    IQTSDGTWYG NWGVCFTYGT WFALGGLAAA GKTYNSCLAM RKAVDFLLRI 650
    QKDDGGWGES YLSCPEKKYV PLEANHSNLV HTAWAMMALV HAGQMDRDPT 700
    PLHRAAKLMI NSQLEDGDFP QQEITGVFNR NCMLHYAAYR NIYPLWALAE 750
    YCRRVPLPS 759
    Length:759
    Mass (Da):87,523
    Last modified:November 13, 2007 - v1
    Checksum:i8F2939D76613A645
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB263203 mRNA. Translation: BAF80441.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB263203 mRNA. Translation: BAF80441.1 .

    3D structure databases

    ProteinModelPortali A8C980.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-14453.

    Family and domain databases

    Gene3Di 1.50.10.20. 2 hits.
    InterProi IPR001330. Prenyltrans.
    IPR018333. Squalene_cyclase.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    [Graphical view ]
    Pfami PF00432. Prenyltrans. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48239. SSF48239. 2 hits.
    TIGRFAMsi TIGR01787. squalene_cyclas. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae."
      Basyuni M., Oku H., Tsujimoto E., Kinjo K., Baba S., Takara K.
      FEBS J. 274:5028-5042(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, CATALYTIC ACTIVITY.
      Tissue: Leaf.

    Entry informationi

    Entry nameiGERS_RHISY
    AccessioniPrimary (citable) accession number: A8C980
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 19, 2011
    Last sequence update: November 13, 2007
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3