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A8C980 (GERS_RHISY) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Germanicol synthase

Short name=RsM1
EC=5.4.99.34
Gene names
Name:M1
OrganismRhizophora stylosa (Bakau) (Red mangrove)
Taxonomic identifier98588 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesRhizophoraceaeRhizophora

Protein attributes

Sequence length759 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Multifunctional triterpene synthase producing germanicol, beta-amyrin and lupeol in the ratio 63:33:4. Ref.1

Catalytic activity

(3S)-2,3-epoxy-2,3-dihydrosqualene = germanicol. Ref.1

Sequence similarities

Belongs to the terpene cyclase/mutase family.

Ontologies

Keywords
   DomainRepeat
   Molecular functionIsomerase
Gene Ontology (GO)
   Molecular_functionintramolecular transferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 759759Germanicol synthase
PRO_0000412987

Sequences

Sequence LengthMass (Da)Tools
A8C980 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 8F2939D76613A645

FASTA75987,523
        10         20         30         40         50         60 
MWRLKIAEGG NDPYLYSTNN YVGRQIWEFD PDAGTPEERA KAEEARQNFY KNRYQVKPSG 

        70         80         90        100        110        120 
DLLWRLQFLR EKNFKQTIPQ VRIEEGEEIT REKATTALRR AVQFFSALQA SDGHWPAENA 

       130        140        150        160        170        180 
GPLFFLPPLV MCMCITGHLD TVFPAEHRKE ILRYIYYHQN EDGGWGLHIE GHSTMFCTAL 

       190        200        210        220        230        240 
NYICMRILGE GPNGGQDDAC TRARKWIHDH GSVTNIPSWG KTWLSILGVY DWSGCNPMPP 

       250        260        270        280        290        300 
EFWMLPSFLP MHPAKMWCYC RMVYMPMSYL YGKRFVGLIT PLIQQLREEL FTQPYDQINW 

       310        320        330        340        350        360 
KKNCHQCAPE DLYYPHPFIQ DLIWDCLYIS MEPLLTRWPL NMIIRKKALE LTMKHIHYED 

       370        380        390        400        410        420 
GSSRYITIGC VEKVLCMLAC WVEDPNGDYF KKHLARIPDY IWVAEDGMKM QSFGSQQWDT 

       430        440        450        460        470        480 
GFAIQALLAT NLTDEIGGVL RRGHDFIKKS QVQDNPSGDF KSMYRHISKG SWTFSDQDHG 

       490        500        510        520        530        540 
WQVSDCTAEG LKCCLLFSMM PPEIVGEHME PERLYDSVNV LLSLQSKNGG LSAWEPAGAQ 

       550        560        570        580        590        600 
DWLELLNPTE FFADIVIEHE YVERTSSAIH ALVLFKKLYP GHRKKEIEDF IAKSVRFLES 

       610        620        630        640        650        660 
IQTSDGTWYG NWGVCFTYGT WFALGGLAAA GKTYNSCLAM RKAVDFLLRI QKDDGGWGES 

       670        680        690        700        710        720 
YLSCPEKKYV PLEANHSNLV HTAWAMMALV HAGQMDRDPT PLHRAAKLMI NSQLEDGDFP 

       730        740        750 
QQEITGVFNR NCMLHYAAYR NIYPLWALAE YCRRVPLPS 

« Hide

References

[1]"Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae."
Basyuni M., Oku H., Tsujimoto E., Kinjo K., Baba S., Takara K.
FEBS J. 274:5028-5042(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, CATALYTIC ACTIVITY.
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB263203 mRNA. Translation: BAF80441.1.

3D structure databases

ProteinModelPortalA8C980.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-14453.

Family and domain databases

Gene3D1.50.10.20. 2 hits.
InterProIPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view]
PfamPF00432. Prenyltrans. 1 hit.
[Graphical view]
SUPFAMSSF48239. SSF48239. 2 hits.
TIGRFAMsTIGR01787. squalene_cyclas. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGERS_RHISY
AccessionPrimary (citable) accession number: A8C980
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: November 13, 2007
Last modified: April 16, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families