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Protein
Submitted name:

Spinous and karyoplasmic protein

Gene

Zmynd8

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • modulation of excitatory postsynaptic potential Source: RGD
  • negative regulation of cell migration Source: Ensembl
  • negative regulation of transcription from RNA polymerase II promoter by histone modification Source: Ensembl
  • positive regulation of dendritic spine development Source: RGD
  • positive regulation of dendritic spine maintenance Source: RGD
  • positive regulation of filopodium assembly Source: RGD
  • regulation of postsynaptic density protein 95 clustering Source: RGD
  • regulation of transcription, DNA-templated Source: GO_Central

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Spinous and karyoplasmic proteinImported
Submitted name:
Zinc finger, MYND-type-containing 8Imported
Gene namesi
Name:Zmynd8Imported
Synonyms:SpikarImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1309544 Zmynd8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PeptideAtlasiA8C4G9

Expressioni

Gene expression databases

BgeeiENSRNOG00000019154
ExpressionAtlasiA8C4G9 baseline and differential

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
Dbn1Q072669EBI-9004258,EBI-918187

GO - Molecular functioni

Protein-protein interaction databases

IntActiA8C4G9, 1 interactor
STRINGi10116.ENSRNOP00000061219

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 133PHD-typeInterPro annotationAdd BLAST46
Domaini165 – 235BromoInterPro annotationAdd BLAST71
Domaini277 – 327PWWPInterPro annotationAdd BLAST51
Domaini1038 – 1072MYND-typeInterPro annotationAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili517 – 537Sequence analysisAdd BLAST21
Coiled coili839 – 862Sequence analysisAdd BLAST24
Coiled coili970 – 1034Sequence analysisAdd BLAST65

Keywords - Domaini

BromodomainPROSITE-ProRule annotation, Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410ITRI Eukaryota
ENOG410XSDA LUCA
GeneTreeiENSGT00910000144099
HOGENOMiHOG000230951
HOVERGENiHBG031823
OMAiSSKSSCW
OrthoDBiEOG091G0B2W

Family and domain databases

CDDicd05508 Bromo_RACK7, 1 hit
cd05841 BS69_related, 1 hit
Gene3Di1.20.920.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR000313 PWWP_dom
IPR037967 RACK7_Bromo_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR021931 ZMYND8
IPR035505 ZMYND8/11_PWWP
IPR011011 Znf_FYVE_PHD
IPR002893 Znf_MYND
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PF12064 DUF3544, 1 hit
PF00855 PWWP, 1 hit
SMARTiView protein in SMART
SM00297 BROMO, 1 hit
SM00249 PHD, 1 hit
SM00293 PWWP, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50014 BROMODOMAIN_2, 1 hit
PS50812 PWWP, 1 hit
PS01360 ZF_MYND_1, 1 hit
PS50865 ZF_MYND_2, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

Sequencei

Sequence statusi: Complete.

A8C4G9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDISTRSKDP GSTERTAQKR KVPSPPHSSN GHSPQDSSTS PIKKKKKPGL
60 70 80 90 100
LNSSSKDQSE LRHGPFYYMK QPLTTDPVDV VPQDGRNDFY CWVCHREGQV
110 120 130 140 150
LCCELCPRVY HAKCLRLTSE PEGDWFCPEC EKITVAECIE TQSKAMTMLT
160 170 180 190 200
IEQLSYLLKF AIQKMKQPGT DAFQKPVPLE QHPDYAEYIF HPMDLCTLEK
210 220 230 240 250
NAKKKMYGCT EAFLADAKWI LHNCIIYNGG NHKLTQIAKV VIKICEHEMN
260 270 280 290 300
EIEVCPECYL AACQKRDNWF CEPCSNPHPL VWAKLKGFPF WPAKALRDKD
310 320 330 340 350
GQVDARFFGQ HDRAWVPVNN CYLMSKEIPF SVKKTKSIFN SAMQEMEVYV
360 370 380 390 400
ENIRKKFGVF NYSPFRTPYT PNSQYQMLLD PSNPSAGTAK TDKQEKVKLN
410 420 430 440 450
FDMTASPKII LSKPLLSGGA GRRISLSDMP RSPTSTNSSV HTGSDVEQDP
460 470 480 490 500
EKKAPSSHFS ASEESMDFLD KSTASPASTK TGQAGSLSGS PKPFSPQAPT
510 520 530 540 550
PIMTKPDKTS TATTGSILNL NLDRSKAEMD LKELSESVQQ QSAPVPLISP
560 570 580 590 600
KRQIRSRFQL NLDKTIESCK AQLGINEISE DVYTAVEHSD SEDSEKSESS
610 620 630 640 650
DSEYVSDEEQ KPKNEPEDPE DKEGSRVDKE APAIKRKPKP SNQVEVKEEV
660 670 680 690 700
KSNSPVGEKV DPAPAKDKAS PEPEKDFAEK AKPSPHPTKD KLKGKDETDS
710 720 730 740 750
PTVHLGLDSD SESELVIDLG EDPSGREGRK NKKEPKVPSP KQDAIGKPPP
760 770 780 790 800
PTPAGNQSPP ETPVLTRSAT QAPAAGVTVA ATTSTMSTVT VTAPATAAVT
810 820 830 840 850
GSPVKKQRPL LPKETVPAVQ RVVWNASSKF QTSSQKWHMQ KIQRQQQQQQ
860 870 880 890 900
QQQQQQQSQQ QQPQSSQGTR YQTRQAVKAV QQKEVTQSPS TSTITLVTST
910 920 930 940 950
QPAALVSSSG SASTLASVIN ADLPIATASA DVAADIAKYT SKMMDAIKGT
960 970 980 990 1000
MTEIYNDLSK NTTGSTIAEI RRLRIEIEKL QWLHQQELAE MKHNLELTMA
1010 1020 1030 1040 1050
EMRQSLEQER DRLIAEVKKQ LELEKQQAVD ETKKKQWCAN CKKEAIFYCC
1060 1070 1080 1090 1100
WNTSYCDYPC QQAHWPEHMK SCTQSATAPQ QEADAEANQE TGNKTSQGSS
1110 1120 1130 1140 1150
SNTQSAPSEP ASTPKEKETS SSSSNSSSTE KSKDSNSTLD LSGSRETPSS
1160 1170 1180 1190 1200
ILLGSNQGSD HSRSSKAGLW SSSEEKRGSS RSEHSAGTST KNLMPKESRE

SRLDTFWD
Length:1,208
Mass (Da):133,605
Last modified:November 13, 2007 - v1
Checksum:iB25CB7EF2D41B352
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054585 Genomic DNA No translation available.
AABR07054586 Genomic DNA No translation available.
AB074010 mRNA Translation: BAF81490.1
RefSeqiNP_001094308.1, NM_001100838.1
UniGeneiRn.219272
Rn.23808

Genome annotation databases

EnsembliENSRNOT00000068328; ENSRNOP00000061219; ENSRNOG00000019154
GeneIDi296374
KEGGirno:296374

Similar proteinsi

Entry informationi

Entry nameiA8C4G9_RAT
AccessioniPrimary (citable) accession number: A8C4G9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: May 23, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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