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A8B2K2

- A8B2K2_GIAIC

UniProt

A8B2K2 - A8B2K2_GIAIC

Protein
Submitted name:

Ribose 5-phosphate isomerase

Gene

GL50803_27614

Organism
Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (13 Nov 2007)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei34 – 341Sulfate 1Imported
    Binding sitei77 – 771Sulfate 5Imported
    Binding sitei80 – 801Sulfate 4; via amide nitrogenImported
    Binding sitei99 – 991Sulfate 5Imported

    GO - Molecular functioni

    1. ribose-5-phosphate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pentose-phosphate shunt Source: InterPro

    Keywords - Molecular functioni

    IsomeraseImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Ribose 5-phosphate isomeraseImported (EC:5.3.1.6Imported)
    Gene namesi
    ORF Names:GL50803_27614Imported
    OrganismiGiardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)Imported
    Taxonomic identifieri184922 [NCBI]
    Taxonomic lineageiEukaryotaDiplomonadidaHexamitidaeGiardiinaeGiardia
    ProteomesiUP000001548: Unassembled WGS sequence

    Organism-specific databases

    EuPathDBiGiardiaDB:GL50803_27614.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3S5PX-ray2.30A/B1-145[»]
    ProteinModelPortaliA8B2K2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni12 – 154Sulfate 1 bindingImported
    Regioni20 – 212Sulfate 2 bindingImported
    Regioni66 – 716Sulfate 3 bindingImported
    Regioni67 – 704Sulfate 4 bindingImported

    Phylogenomic databases

    KOiK01808.
    OMAiCRPEFAT.

    Family and domain databases

    Gene3Di3.40.1400.10. 1 hit.
    InterProiIPR004785. RpiB.
    IPR003500. RpiB_LacA_LacB.
    [Graphical view]
    PANTHERiPTHR30345. PTHR30345. 1 hit.
    PfamiPF02502. LacAB_rpiB. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005384. RpiB_LacA_B. 1 hit.
    SUPFAMiSSF89623. SSF89623. 1 hit.
    TIGRFAMsiTIGR01120. rpiB. 1 hit.
    TIGR00689. rpiB_lacA_lacB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A8B2K2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKVAFASDHG GRDLRMFLQQ RASAHGYEVM DLGTESDASV DYPDFAKIGC    50
    EAVTSGRADC CILVCGTGIG ISIAANKMKG IRCALCSTEY DAEMARKHNN 100
    ANALALGGRT TGPEVAASIL SRFLSTNFEG GRHAARIAKI SAMEE 145
    Length:145
    Mass (Da):15,349
    Last modified:November 13, 2007 - v1
    Checksum:iD629E3DBD494E116
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACB02000001 Genomic DNA. Translation: EDO82317.1.
    RefSeqiXP_001709991.1. XM_001709939.1.

    Genome annotation databases

    EnsemblProtistsiEDO82317; EDO82317; GL50803_27614.
    GeneIDi5702915.
    KEGGigla:GL50803_27614.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACB02000001 Genomic DNA. Translation: EDO82317.1 .
    RefSeqi XP_001709991.1. XM_001709939.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3S5P X-ray 2.30 A/B 1-145 [» ]
    ProteinModelPortali A8B2K2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi EDO82317 ; EDO82317 ; GL50803_27614 .
    GeneIDi 5702915.
    KEGGi gla:GL50803_27614.

    Organism-specific databases

    EuPathDBi GiardiaDB:GL50803_27614.

    Phylogenomic databases

    KOi K01808.
    OMAi CRPEFAT.

    Family and domain databases

    Gene3Di 3.40.1400.10. 1 hit.
    InterProi IPR004785. RpiB.
    IPR003500. RpiB_LacA_LacB.
    [Graphical view ]
    PANTHERi PTHR30345. PTHR30345. 1 hit.
    Pfami PF02502. LacAB_rpiB. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005384. RpiB_LacA_B. 1 hit.
    SUPFAMi SSF89623. SSF89623. 1 hit.
    TIGRFAMsi TIGR01120. rpiB. 1 hit.
    TIGR00689. rpiB_lacA_lacB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 50803 / WB clone C6Imported.
    2. "Crystal structure of ribose-5-phosphate isomerase B RpiB from Giardia lamblia."
      Seattle Structural Genomics Center for Infectious Disease (SSGCID)
      Edwards T.E., Abendroth J.
      Submitted (MAY-2011) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).

    Entry informationi

    Entry nameiA8B2K2_GIAIC
    AccessioniPrimary (citable) accession number: A8B2K2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 13, 2007
    Last sequence update: November 13, 2007
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3