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A8B2K2

- A8B2K2_GIAIC

UniProt

A8B2K2 - A8B2K2_GIAIC

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Protein
Submitted name:

Ribose 5-phosphate isomerase

Gene
GL50803_27614
Organism
Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei34 – 341Sulfate 1Imported
Binding sitei77 – 771Sulfate 5Imported
Binding sitei80 – 801Sulfate 4; via amide nitrogenImported
Binding sitei99 – 991Sulfate 5Imported

GO - Molecular functioni

  1. ribose-5-phosphate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. pentose-phosphate shunt Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Ribose 5-phosphate isomeraseImported (EC:5.3.1.6Imported)
Gene namesi
ORF Names:GL50803_27614Imported
OrganismiGiardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)
Taxonomic identifieri184922 [NCBI]
Taxonomic lineageiEukaryotaDiplomonadidaHexamitidaeGiardiinaeGiardia
ProteomesiUP000001548: Unassembled WGS sequence

Organism-specific databases

EuPathDBiGiardiaDB:GL50803_27614.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3S5PX-ray2.30A/B1-145[»]
ProteinModelPortaliA8B2K2.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni12 – 154Sulfate 1 bindingImported
Regioni20 – 212Sulfate 2 bindingImported
Regioni66 – 716Sulfate 3 bindingImported
Regioni67 – 704Sulfate 4 bindingImported

Phylogenomic databases

KOiK01808.
OMAiCRPEFAT.

Family and domain databases

Gene3Di3.40.1400.10. 1 hit.
InterProiIPR004785. RpiB.
IPR003500. RpiB_LacA_LacB.
[Graphical view]
PANTHERiPTHR30345. PTHR30345. 1 hit.
PfamiPF02502. LacAB_rpiB. 1 hit.
[Graphical view]
PIRSFiPIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMiSSF89623. SSF89623. 1 hit.
TIGRFAMsiTIGR01120. rpiB. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.

Sequencei

Sequence statusi: Complete.

A8B2K2-1 [UniParc]FASTAAdd to Basket

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MKVAFASDHG GRDLRMFLQQ RASAHGYEVM DLGTESDASV DYPDFAKIGC    50
EAVTSGRADC CILVCGTGIG ISIAANKMKG IRCALCSTEY DAEMARKHNN 100
ANALALGGRT TGPEVAASIL SRFLSTNFEG GRHAARIAKI SAMEE 145
Length:145
Mass (Da):15,349
Last modified:November 13, 2007 - v1
Checksum:iD629E3DBD494E116
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACB02000001 Genomic DNA. Translation: EDO82317.1.
RefSeqiXP_001709991.1. XM_001709939.1.

Genome annotation databases

EnsemblProtistsiEDO82317; EDO82317; GL50803_27614.
GeneIDi5702915.
KEGGigla:GL50803_27614.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACB02000001 Genomic DNA. Translation: EDO82317.1 .
RefSeqi XP_001709991.1. XM_001709939.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3S5P X-ray 2.30 A/B 1-145 [» ]
ProteinModelPortali A8B2K2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi EDO82317 ; EDO82317 ; GL50803_27614 .
GeneIDi 5702915.
KEGGi gla:GL50803_27614.

Organism-specific databases

EuPathDBi GiardiaDB:GL50803_27614.

Phylogenomic databases

KOi K01808.
OMAi CRPEFAT.

Family and domain databases

Gene3Di 3.40.1400.10. 1 hit.
InterProi IPR004785. RpiB.
IPR003500. RpiB_LacA_LacB.
[Graphical view ]
PANTHERi PTHR30345. PTHR30345. 1 hit.
Pfami PF02502. LacAB_rpiB. 1 hit.
[Graphical view ]
PIRSFi PIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMi SSF89623. SSF89623. 1 hit.
TIGRFAMsi TIGR01120. rpiB. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 50803 / WB clone C6.
  2. "Crystal structure of ribose-5-phosphate isomerase B RpiB from Giardia lamblia."
    Seattle Structural Genomics Center for Infectious Disease (SSGCID)
    Edwards T.E., Abendroth J.
    Submitted (MAY-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).

Entry informationi

Entry nameiA8B2K2_GIAIC
AccessioniPrimary (citable) accession number: A8B2K2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: September 3, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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