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A8B2K2

- A8B2K2_GIAIC

UniProt

A8B2K2 - A8B2K2_GIAIC

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Protein
Submitted name:

Ribose 5-phosphate isomerase

Gene

GL50803_27614

Organism
Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei34 – 341Sulfate 1Imported
Binding sitei77 – 771Sulfate 5Imported
Binding sitei80 – 801Sulfate 4; via amide nitrogenImported
Binding sitei99 – 991Sulfate 5Imported

GO - Molecular functioni

  1. ribose-5-phosphate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. pentose-phosphate shunt Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Ribose 5-phosphate isomeraseImported (EC:5.3.1.6Imported)
Gene namesi
ORF Names:GL50803_27614Imported
OrganismiGiardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)Imported
Taxonomic identifieri184922 [NCBI]
Taxonomic lineageiEukaryotaDiplomonadidaHexamitidaeGiardiinaeGiardia
ProteomesiUP000001548: Unassembled WGS sequence

Organism-specific databases

EuPathDBiGiardiaDB:GL50803_27614.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3S5PX-ray2.30A/B1-145[»]
ProteinModelPortaliA8B2K2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni12 – 154Sulfate 1 bindingImported
Regioni20 – 212Sulfate 2 bindingImported
Regioni66 – 716Sulfate 3 bindingImported
Regioni67 – 704Sulfate 4 bindingImported

Phylogenomic databases

InParanoidiA8B2K2.
KOiK01808.
OMAiCRPEFAT.

Family and domain databases

Gene3Di3.40.1400.10. 1 hit.
InterProiIPR004785. RpiB.
IPR003500. RpiB_LacA_LacB.
[Graphical view]
PANTHERiPTHR30345. PTHR30345. 1 hit.
PfamiPF02502. LacAB_rpiB. 1 hit.
[Graphical view]
PIRSFiPIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMiSSF89623. SSF89623. 1 hit.
TIGRFAMsiTIGR01120. rpiB. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.

Sequencei

Sequence statusi: Complete.

A8B2K2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVAFASDHG GRDLRMFLQQ RASAHGYEVM DLGTESDASV DYPDFAKIGC
60 70 80 90 100
EAVTSGRADC CILVCGTGIG ISIAANKMKG IRCALCSTEY DAEMARKHNN
110 120 130 140
ANALALGGRT TGPEVAASIL SRFLSTNFEG GRHAARIAKI SAMEE
Length:145
Mass (Da):15,349
Last modified:November 13, 2007 - v1
Checksum:iD629E3DBD494E116
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACB02000001 Genomic DNA. Translation: EDO82317.1.
RefSeqiXP_001709991.1. XM_001709939.1.

Genome annotation databases

EnsemblProtistsiEDO82317; EDO82317; GL50803_27614.
GeneIDi5702915.
KEGGigla:GL50803_27614.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACB02000001 Genomic DNA. Translation: EDO82317.1 .
RefSeqi XP_001709991.1. XM_001709939.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3S5P X-ray 2.30 A/B 1-145 [» ]
ProteinModelPortali A8B2K2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi EDO82317 ; EDO82317 ; GL50803_27614 .
GeneIDi 5702915.
KEGGi gla:GL50803_27614.

Organism-specific databases

EuPathDBi GiardiaDB:GL50803_27614.

Phylogenomic databases

InParanoidi A8B2K2.
KOi K01808.
OMAi CRPEFAT.

Family and domain databases

Gene3Di 3.40.1400.10. 1 hit.
InterProi IPR004785. RpiB.
IPR003500. RpiB_LacA_LacB.
[Graphical view ]
PANTHERi PTHR30345. PTHR30345. 1 hit.
Pfami PF02502. LacAB_rpiB. 1 hit.
[Graphical view ]
PIRSFi PIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMi SSF89623. SSF89623. 1 hit.
TIGRFAMsi TIGR01120. rpiB. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 50803 / WB clone C6Imported.
  2. "Crystal structure of ribose-5-phosphate isomerase B RpiB from Giardia lamblia."
    Seattle Structural Genomics Center for Infectious Disease (SSGCID)
    Edwards T.E., Abendroth J.
    Submitted (MAY-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).

Entry informationi

Entry nameiA8B2K2_GIAIC
AccessioniPrimary (citable) accession number: A8B2K2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: October 29, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3