Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A8B2K2 (A8B2K2_GIAIC) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
EC=5.3.1.6 EMBL EDO82317.1
Gene names
ORF Names:GL50803_27614 EMBL EDO82317.1
OrganismGiardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia) [Reference proteome]
Taxonomic identifier184922 [NCBI]
Taxonomic lineageEukaryotaDiplomonadidaHexamitidaeGiardiinaeGiardia

Protein attributes

Sequence length145 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
   Molecular functionIsomerase EMBL EDO82317.1
   Technical term3D-structure PDB 3S5P
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpentose-phosphate shunt

Inferred from electronic annotation. Source: InterPro

   Molecular_functionribose-5-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region12 – 154Sulfate 1 binding PDB 3S5P
Region20 – 212Sulfate 2 binding PDB 3S5P
Region66 – 716Sulfate 3 binding PDB 3S5P
Region67 – 704Sulfate 4 binding PDB 3S5P

Sites

Binding site341Sulfate 1 PDB 3S5P
Binding site771Sulfate 5 PDB 3S5P
Binding site801Sulfate 4; via amide nitrogen PDB 3S5P
Binding site991Sulfate 5 PDB 3S5P

Sequences

Sequence LengthMass (Da)Tools
A8B2K2 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: D629E3DBD494E116

FASTA14515,349
        10         20         30         40         50         60 
MKVAFASDHG GRDLRMFLQQ RASAHGYEVM DLGTESDASV DYPDFAKIGC EAVTSGRADC 

        70         80         90        100        110        120 
CILVCGTGIG ISIAANKMKG IRCALCSTEY DAEMARKHNN ANALALGGRT TGPEVAASIL 

       130        140 
SRFLSTNFEG GRHAARIAKI SAMEE 

« Hide

References

« Hide 'large scale' references
[1]"Genomic minimalism in the early diverging intestinal parasite Giardia lamblia."
Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D., Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J., Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U., Lasek-Nesselquist E. expand/collapse author list , Manning G., Nigam A., Nixon J.E.J., Palm D., Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J., Svard S.G., Sogin M.L.
Science 317:1921-1926(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 50803 / WB clone C6.
[2]"Crystal structure of ribose-5-phosphate isomerase B RpiB from Giardia lamblia."
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Edwards T.E., Abendroth J.
Submitted (MAY-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) IN COMPLEX WITH SULFATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACB02000001 Genomic DNA. Translation: EDO82317.1.
RefSeqXP_001709991.1. XM_001709939.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3S5PX-ray2.30A/B1-145[»]
ProteinModelPortalA8B2K2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsEDO82317; EDO82317; GL50803_27614.
GeneID5702915.
KEGGgla:GL50803_27614.

Organism-specific databases

EuPathDBGiardiaDB:GL50803_27614.

Phylogenomic databases

KOK01808.
OMAETHHANQ.
ProtClustDBPTZ00215.

Family and domain databases

Gene3D3.40.1400.10. 1 hit.
InterProIPR004785. RpiB.
IPR003500. RpiB_LacA_LacB.
[Graphical view]
PANTHERPTHR30345. PTHR30345. 1 hit.
PfamPF02502. LacAB_rpiB. 1 hit.
[Graphical view]
PIRSFPIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMSSF89623. SSF89623. 1 hit.
TIGRFAMsTIGR01120. rpiB. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8B2K2_GIAIC
AccessionPrimary (citable) accession number: A8B2K2
Entry history
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: November 13, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)