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A8AYH3 (GLGB_STRGC) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:SGO_1554
OrganismStreptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288) [Complete proteome] [HAMAP]
Taxonomic identifier29390 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length633 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6336331,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_1000083072

Sites

Active site3041Nucleophile By similarity
Active site3551Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A8AYH3 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: B7812DCCC9446826

FASTA63373,986
        10         20         30         40         50         60 
MDKNEALRTF TTGENFHLQH YLGAHQEEVD GKVGYSFRVW APNAQSVHLI GDFTNWYENQ 

        70         80         90        100        110        120 
IPMARNEAGV WEVFTDLPKE GDIYKYNVKR SSGQEILKID PLAVYLEERP GTGAVIRTIP 

       130        140        150        160        170        180 
EKKWKDGLWL ARRKRWGFFS RPVNIYEVHA GSWKRNEDGS PYSFAQLKED LIPYLVEMNY 

       190        200        210        220        230        240 
THVEFMPLMA HPLGLSWGYQ LMGYFAFEHT YGTPEEFQDF VEECHLNNIG VIVDWVPGHF 

       250        260        270        280        290        300 
TINDDALAYY DGTPTFEYQD HDRAHNYGWG ALNFDLGKNQ VQSFLISSIK FWIDFYHLDG 

       310        320        330        340        350        360 
IRVDAVSNML YLDYDSGPWQ PNKDGGNRNY EGYYFLQRLN TVIKLAHPDV MMIAEESSSG 

       370        380        390        400        410        420 
TKITGMRELG GLGFDYKWNM GWMNDILRFY EEDPIYRKYD FNLVTFSFMY VFSENFLLPF 

       430        440        450        460        470        480 
SHDEVVHGKK SLMHKMWGDR YNQFAGLRNL LTYQICHPGK KLLFMGSEFG QFLEWKSEEQ 

       490        500        510        520        530        540 
LEWSNLDDEM NKKMQGFTAT LNAFYKDNRP LWEIDLSYDG IEIIDADNVD QSVLSFIRKT 

       550        560        570        580        590        600 
EKGDMLICVF NMAPVERKNF TIGVPVAAVY EEVWNTELEE WGGVWKEHNE TVQSQEGLWK 

       610        620        630 
DYPQTLTFTL PALGASIWKI KRRIKSKSTK NKK 

« Hide

References

[1]"Genome-wide transcriptional changes in Streptococcus gordonii in response to competence signaling peptide."
Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.
J. Bacteriol. 189:7799-7807(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Challis / ATCC 35105 / CH1 / DL1 / V288.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000725 Genomic DNA. Translation: ABV10912.1.
RefSeqYP_001450833.1. NC_009785.1.

3D structure databases

ProteinModelPortalA8AYH3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING467705.SGO_1554.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV10912; ABV10912; SGO_1554.
GeneID5599664.
KEGGsgo:SGO_1554.
PATRIC19661058. VBIStrGor124371_1530.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAAKLLFMG.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycSGOR467705:GH3R-1553-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_STRGC
AccessionPrimary (citable) accession number: A8AYH3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: October 23, 2007
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries