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Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathway: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciSGOR467705:GH3R-1550-MONOMER.
UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:SGO_1551
OrganismiStreptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288)
Taxonomic identifieri29390 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001131 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Glycogen synthasePRO_1000081332Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi467705.SGO_1551.

Structurei

3D structure databases

ProteinModelPortaliA8AYH0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

A8AYH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILFVAAEG APFSKTGGLG DVIGALPKSL VKHGHQVGVI LPYYDMTDAK
60 70 80 90 100
FGDQVEDLFY FEVSVGWRRQ YVGVKRLVLN GVSFYFIDNQ HYFFRGHVYG
110 120 130 140 150
DFDDGERFAY FQLAAVELME RIDFIPDVLH VHDYHTAMIP FLVKEKYHWI
160 170 180 190 200
QAYRNIKTVL TIHNLEFQGQ FPDSMLWELF GVGYERYADG TLRWNDCLNW
210 220 230 240 250
MKAGILYADR VTTVSPSYAG EIRTPEFGCN LDQILRMESG KLVGIVNGID
260 270 280 290 300
TEIYNPETDP LLAHHFDKSD LSGKLENKRA LQERVGLPVR DDVPLVGIVS
310 320 330 340 350
RLTRQKGFDL VVEELHNFLQ QDVQIILLGT GDPAFEQAFA WFGQAYPDKL
360 370 380 390 400
SANILFDVGL AQEIYAASDI FLMPSRFEPC GLSQMMAMRY GTLPLVHEVG
410 420 430 440 450
GLRDTVEPYN VYTGQGTGFS FNNFSGYWLS WTFKEALNLY THDKEAWKSM
460 470
QEQAMERDFS WDTASLAYSD LYQSLL
Length:476
Mass (Da):54,396
Last modified:October 23, 2007 - v1
Checksum:i0811B28F5B5256B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000725 Genomic DNA. Translation: ABV10483.1.
RefSeqiYP_001450830.1. NC_009785.1.

Genome annotation databases

EnsemblBacteriaiABV10483; ABV10483; SGO_1551.
KEGGisgo:SGO_1551.
PATRICi19661052. VBIStrGor124371_1527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000725 Genomic DNA. Translation: ABV10483.1.
RefSeqiYP_001450830.1. NC_009785.1.

3D structure databases

ProteinModelPortaliA8AYH0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi467705.SGO_1551.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV10483; ABV10483; SGO_1551.
KEGGisgo:SGO_1551.
PATRICi19661052. VBIStrGor124371_1527.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciSGOR467705:GH3R-1550-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome-wide transcriptional changes in Streptococcus gordonii in response to competence signaling peptide."
    Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.
    J. Bacteriol. 189:7799-7807(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Challis / ATCC 35105 / CH1 / DL1 / V288.

Entry informationi

Entry nameiGLGA_STRGC
AccessioniPrimary (citable) accession number: A8AYH0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: October 23, 2007
Last modified: June 24, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.