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A8AXN4

- DEOD_STRGC

UniProt

A8AXN4 - DEOD_STRGC

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Protein

Purine nucleoside phosphorylase DeoD-type

Gene

deoD

Organism
Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.UniRule annotation
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. purine-nucleoside phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. purine nucleoside metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciSGOR467705:GH3R-1258-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Purine nucleoside phosphorylase DeoD-typeUniRule annotation (EC:2.4.2.1UniRule annotation)
Short name:
PNPUniRule annotation
Gene namesi
Name:deoDUniRule annotation
Ordered Locus Names:SGO_1260
OrganismiStreptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288)
Taxonomic identifieri29390 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001131: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 237237Purine nucleoside phosphorylase DeoD-typePRO_1000186224Add
BLAST

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi467705.SGO_1260.

Structurei

3D structure databases

ProteinModelPortaliA8AXN4.
SMRiA8AXN4. Positions 1-232.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PNP/UDP phosphorylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0813.
HOGENOMiHOG000274896.
KOiK03784.
OMAiFGMTTHV.
OrthoDBiEOG6BKJC5.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8AXN4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSIHIAAQQG EIADKILLPG DPLRAKFIAE NFLEDAVCFN EVRNMFGYTG
60 70 80 90 100
TYKGHRVSVM GTGMGMPSIS IYARELIVDY GVKKLIRVGT AGSLNEDVHV
110 120 130 140 150
RELVLAQAAA TNSNIIRNDW PQYDFPQIAS FDLLDKAYHI AKDLGMTTHV
160 170 180 190 200
GNVLSSDVFY SNYFEKNIEL GKWGVKAVEM EAAALYYLAA QHHVDALAIM
210 220 230
TISDSLVNPE EDTTAEERQN TFTDMMKVGL ETLIAEA
Length:237
Mass (Da):26,243
Last modified:October 23, 2007 - v1
Checksum:iA866546231F843BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000725 Genomic DNA. Translation: ABV10410.1.
RefSeqiYP_001450544.1. NC_009785.1.

Genome annotation databases

EnsemblBacteriaiABV10410; ABV10410; SGO_1260.
GeneIDi5599062.
KEGGisgo:SGO_1260.
PATRICi19660473. VBIStrGor124371_1240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000725 Genomic DNA. Translation: ABV10410.1 .
RefSeqi YP_001450544.1. NC_009785.1.

3D structure databases

ProteinModelPortali A8AXN4.
SMRi A8AXN4. Positions 1-232.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 467705.SGO_1260.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABV10410 ; ABV10410 ; SGO_1260 .
GeneIDi 5599062.
KEGGi sgo:SGO_1260.
PATRICi 19660473. VBIStrGor124371_1240.

Phylogenomic databases

eggNOGi COG0813.
HOGENOMi HOG000274896.
KOi K03784.
OMAi FGMTTHV.
OrthoDBi EOG6BKJC5.

Enzyme and pathway databases

BioCyci SGOR467705:GH3R-1258-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1580. 1 hit.
HAMAPi MF_01627. Pur_nucleosid_phosp.
InterProi IPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view ]
PANTHERi PTHR21234. PTHR21234. 1 hit.
Pfami PF01048. PNP_UDP_1. 1 hit.
[Graphical view ]
SUPFAMi SSF53167. SSF53167. 1 hit.
TIGRFAMsi TIGR00107. deoD. 1 hit.
PROSITEi PS01232. PNP_UDP_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome-wide transcriptional changes in Streptococcus gordonii in response to competence signaling peptide."
    Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.
    J. Bacteriol. 189:7799-7807(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Challis / ATCC 35105 / CH1 / DL1 / V288.

Entry informationi

Entry nameiDEOD_STRGC
AccessioniPrimary (citable) accession number: A8AXN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: October 23, 2007
Last modified: October 1, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3