ID   WHIA_STRGC              Reviewed;         303 AA.
AC   A8AWT7;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   27-MAR-2024, entry version 97.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   OrderedLocusNames=SGO_0956;
OS   Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 /
OS   DL1 / V288).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=467705;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288;
RX   PubMed=17720781; DOI=10.1128/jb.01023-07;
RA   Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.;
RT   "Genome-wide transcriptional changes in Streptococcus gordonii in response
RT   to competence signaling peptide.";
RL   J. Bacteriol. 189:7799-7807(2007).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; CP000725; ABV09711.1; -; Genomic_DNA.
DR   RefSeq; WP_012000377.1; NC_009785.1.
DR   AlphaFoldDB; A8AWT7; -.
DR   SMR; A8AWT7; -.
DR   STRING; 467705.SGO_0956; -.
DR   KEGG; sgo:SGO_0956; -.
DR   eggNOG; COG1481; Bacteria.
DR   HOGENOM; CLU_053282_0_0_9; -.
DR   Proteomes; UP000001131; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   NCBIfam; TIGR00647; DNA_bind_WhiA; 1.
DR   PANTHER; PTHR37307; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR   PANTHER; PTHR37307:SF1; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; Homing endonucleases; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..303
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376574"
FT   DNA_BIND        272..303
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   303 AA;  33906 MW;  F0FFE3C5C278C1BB CRC64;
     MSFTVKVKEE LLGLGTKSKS ELAAIMKMSG SLGIASQGLT LSITTENAKI ARHIYELLLS
     FYQVKSDIRH HQKTNLRKNR VYTVFLDEKV EDILSDLHLA DAFFGIQEGI DPLILSDDEA
     SRAYLRGAFL SNGSMRDPES GKYQLEIVSV YLDHAQGLAS LMQRFLLDAK TIERKKGAVT
     YLQRAEDIMD FLIVVGAMEA MAEFEAVKIL RETRNDLNRA NNAETANIAR TVTASMKTIN
     NIVKIMETSG LENLPIDLQE VAHLRVNHPD YSIQQLADSL SKPLTKSGVN HRLRKINKIA
     DEL
//